BRD-A14652656_Bucladesine sodium salt_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

91 genes differentially expressed following the BRD-A14652656_Bucladesine sodium salt_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTN1 actinin, alpha 1
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADIRF adipogenesis regulatory factor
AHNAK AHNAK nucleoprotein
AHNAK2 AHNAK nucleoprotein 2
ARL4C ADP-ribosylation factor-like 4C
CAV2 caveolin 2
CFD complement factor D (adipsin)
CST3 cystatin C
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DLD dihydrolipoamide dehydrogenase
FABP4 fatty acid binding protein 4, adipocyte
FABP5 fatty acid binding protein 5 (psoriasis-associated)
G0S2 G0/G1 switch 2
GAS2L1 growth arrest-specific 2 like 1
GCH1 GTP cyclohydrolase 1
GHR growth hormone receptor
GPM6B glycoprotein M6B
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFI27 interferon, alpha-inducible protein 27
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KLF5 Kruppel-like factor 5 (intestinal)
LEPR leptin receptor
METRN meteorin, glial cell differentiation regulator
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PODXL podocalyxin-like
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRSS2 protease, serine, 2 (trypsin 2)
PRSS3 protease, serine, 3
S100A2 S100 calcium binding protein A2
SATB2 SATB homeobox 2
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SORD sorbitol dehydrogenase
SRPX sushi-repeat containing protein, X-linked
SYNGR3 synaptogyrin 3
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF3 trefoil factor 3 (intestinal)
THBS1 thrombospondin 1
TM4SF1 transmembrane 4 L six family member 1
TMEM47 transmembrane protein 47
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TSPAN13 tetraspanin 13
TSPAN8 tetraspanin 8
TSPO translocator protein (18kDa)
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ADGRF5 adhesion G protein-coupled receptor F5
AFP alpha-fetoprotein
ANXA4 annexin A4
AREG amphiregulin
CADM1 cell adhesion molecule 1
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
COL4A5 collagen, type IV, alpha 5
CPE carboxypeptidase E
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DLK1 delta-like 1 homolog (Drosophila)
EDNRA endothelin receptor type A
EGR1 early growth response 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
HNMT histamine N-methyltransferase
INSR insulin receptor
KLHDC3 kelch domain containing 3
LPPR1 lipid phosphate phosphatase-related protein type 1
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MBD4 methyl-CpG binding domain protein 4
NARFL nuclear prelamin A recognition factor-like
NID1 nidogen 1
NREP neuronal regeneration related protein
NVL nuclear VCP-like
PEG10 paternally expressed 10
PEG3 paternally expressed 3
PRSS21 protease, serine, 21 (testisin)
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SDC2 syndecan 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFTPC surfactant protein C
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SOX11 SRY (sex determining region Y)-box 11
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TUSC3 tumor suppressor candidate 3
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
VGLL1 vestigial-like family member 1
VTCN1 V-set domain containing T cell activation inhibitor 1