BRD-A14574269_UB 165 fumarate_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

30 genes differentially expressed following the BRD-A14574269_UB 165 fumarate_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALOX5AP arachidonate 5-lipoxygenase-activating protein
BCHE butyrylcholinesterase
BPHL biphenyl hydrolase-like (serine hydrolase)
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCL2 chemokine (C-C motif) ligand 2
CD9 CD9 molecule
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FLOT1 flotillin 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
KRT15 keratin 15, type I
NT5DC2 5'-nucleotidase domain containing 2
RGS1 regulator of G-protein signaling 1
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
S100A8 S100 calcium binding protein A8
SCGB2A1 secretoglobin, family 2A, member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
TCTA T-cell leukemia translocation altered
TDO2 tryptophan 2,3-dioxygenase
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
DMBT1 deleted in malignant brain tumors 1
EXOSC4 exosome component 4
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HOXC6 homeobox C6
REG1A regenerating islet-derived 1 alpha
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TSPAN8 tetraspanin 8