BRD-A14574269_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-A14574269_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA1 annexin A1
ARMT1 acidic residue methyltransferase 1
ATG3 autophagy related 3
BMI1 BMI1 proto-oncogene, polycomb ring finger
CCL13 chemokine (C-C motif) ligand 13
CCND2 cyclin D2
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GSN gelsolin
HOPX HOP homeobox
KRT14 keratin 14, type I
LEPR leptin receptor
NPR3 natriuretic peptide receptor 3
PDZK1 PDZ domain containing 1
PLAGL1 pleiomorphic adenoma gene-like 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PTN pleiotrophin
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RAB2A RAB2A, member RAS oncogene family
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC39A6 solute carrier family 39 (zinc transporter), member 6
TNPO1 transportin 1
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
VAV3 vav 3 guanine nucleotide exchange factor

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
C6ORF62 chromosome 6 open reading frame 62
CA12 carbonic anhydrase XII
CAST calpastatin
CD44 CD44 molecule (Indian blood group)
COL1A1 collagen, type I, alpha 1
COL6A1 collagen, type VI, alpha 1
COLEC12 collectin sub-family member 12
CYBB cytochrome b-245, beta polypeptide
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2
FHL1 four and a half LIM domains 1
FN1 fibronectin 1
GPX2 glutathione peroxidase 2
IPO13 importin 13
KCTD12 potassium channel tetramerization domain containing 12
LAPTM5 lysosomal protein transmembrane 5
MARCKS myristoylated alanine-rich protein kinase C substrate
PLEC plectin
PTPRO protein tyrosine phosphatase, receptor type, O
RCAN1 regulator of calcineurin 1
RPS11 ribosomal protein S11
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPINK1 serine peptidase inhibitor, Kazal type 1
SRPR signal recognition particle receptor (docking protein)
SYT1 synaptotagmin I
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
TMSB15A thymosin beta 15a
TXNIP thioredoxin interacting protein
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZNF91 zinc finger protein 91