BRD-A13807286_S1071_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

105 genes differentially expressed following the BRD-A13807286_S1071_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AEBP1 AE binding protein 1
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
BID BH3 interacting domain death agonist
BLNK B-cell linker
C10ORF10 chromosome 10 open reading frame 10
C1QB complement component 1, q subcomponent, B chain
CD99 CD99 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLC Charcot-Leyden crystal galectin
CLCA1 chloride channel accessory 1
CP ceruloplasmin (ferroxidase)
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EFHD1 EF-hand domain family, member D1
F11R F11 receptor
FTH1 ferritin, heavy polypeptide 1
GLUL glutamate-ammonia ligase
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HMOX1 heme oxygenase 1
HOXD1 homeobox D1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGHD immunoglobulin heavy constant delta
LAMP3 lysosomal-associated membrane protein 3
LIMCH1 LIM and calponin homology domains 1
LRMP lymphoid-restricted membrane protein
MAN1A1 mannosidase, alpha, class 1A, member 1
MARS methionyl-tRNA synthetase
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
PCSK1 proprotein convertase subtilisin/kexin type 1
PEA15 phosphoprotein enriched in astrocytes 15
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTPRO protein tyrosine phosphatase, receptor type, O
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
REEP5 receptor accessory protein 5
S100A8 S100 calcium binding protein A8
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERINC5 serine incorporator 5
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
SULF1 sulfatase 1
TMEM30B transmembrane protein 30B
TPD52 tumor protein D52
TPD52L1 tumor protein D52-like 1
UBE2J1 ubiquitin-conjugating enzyme E2, J1
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VTCN1 V-set domain containing T cell activation inhibitor 1
WARS tryptophanyl-tRNA synthetase
ZNF117 zinc finger protein 117

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
APOLD1 apolipoprotein L domain containing 1
ARL4A ADP-ribosylation factor-like 4A
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BEX1 brain expressed, X-linked 1
BST2 bone marrow stromal cell antigen 2
BTBD3 BTB (POZ) domain containing 3
C9ORF3 chromosome 9 open reading frame 3
CSRP2 cysteine and glycine-rich protein 2
CYTH1 cytohesin 1
CYTL1 cytokine-like 1
DEFB1 defensin, beta 1
EPN2 epsin 2
FBLN1 fibulin 1
HSPB8 heat shock 22kDa protein 8
IFI6 interferon, alpha-inducible protein 6
IGFBP4 insulin-like growth factor binding protein 4
IQGAP2 IQ motif containing GTPase activating protein 2
LBR lamin B receptor
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
NAP1L3 nucleosome assembly protein 1-like 3
NFIB nuclear factor I/B
PAN2 PAN2 poly(A) specific ribonuclease subunit
PDLIM2 PDZ and LIM domain 2 (mystique)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLAC8 placenta-specific 8
PLCB4 phospholipase C, beta 4
PNMA2 paraneoplastic Ma antigen 2
PRR7 proline rich 7 (synaptic)
PRSS23 protease, serine, 23
PSIP1 PC4 and SFRS1 interacting protein 1
RBP1 retinol binding protein 1, cellular
RBPMS RNA binding protein with multiple splicing
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
SCML1 sex comb on midleg-like 1 (Drosophila)
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLIRP SRA stem-loop interacting RNA binding protein
SMAD3 SMAD family member 3
SMS spermine synthase
STK17A serine/threonine kinase 17a
TNC tenascin C
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TSPAN3 tetraspanin 3
TXNIP thioredoxin interacting protein
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1
ZCCHC24 zinc finger, CCHC domain containing 24