BRD-A13650332_Flucloxacillin sodium_HCC515_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

85 genes differentially expressed following the BRD-A13650332_Flucloxacillin sodium_HCC515_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ARID5B AT rich interactive domain 5B (MRF1-like)
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
CD24 CD24 molecule
CLEC2B C-type lectin domain family 2, member B
CPA3 carboxypeptidase A3 (mast cell)
CRELD2 cysteine-rich with EGF-like domains 2
CXADR coxsackie virus and adenovirus receptor
CXCL9 chemokine (C-X-C motif) ligand 9
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DST dystonin
FAM198B family with sequence similarity 198, member B
FAM69A family with sequence similarity 69, member A
FBLN1 fibulin 1
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FN1 fibronectin 1
GCLC glutamate-cysteine ligase, catalytic subunit
GJA1 gap junction protein, alpha 1, 43kDa
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IFT57 intraflagellar transport 57
IGHM immunoglobulin heavy constant mu
LMO3 LIM domain only 3 (rhombotin-like 2)
MAOA monoamine oxidase A
MAP7 microtubule-associated protein 7
MMP2 matrix metallopeptidase 2
MPZL2 myelin protein zero-like 2
NXN nucleoredoxin
OSBPL10 oxysterol binding protein-like 10
PDGFC platelet derived growth factor C
PEG10 paternally expressed 10
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PON3 paraoxonase 3
PPL periplakin
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
QPCT glutaminyl-peptide cyclotransferase
RGCC regulator of cell cycle
RTN1 reticulon 1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SGK1 serum/glucocorticoid regulated kinase 1
TACSTD2 tumor-associated calcium signal transducer 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
UBE2J1 ubiquitin-conjugating enzyme E2, J1
UGDH UDP-glucose 6-dehydrogenase
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
ADD3 adducin 3 (gamma)
ADGRG2 adhesion G protein-coupled receptor G2
ANO1 anoctamin 1, calcium activated chloride channel
BST2 bone marrow stromal cell antigen 2
COL9A3 collagen, type IX, alpha 3
CRIP1 cysteine-rich protein 1 (intestinal)
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL8 chemokine (C-X-C motif) ligand 8
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
EPHA3 EPH receptor A3
FADS1 fatty acid desaturase 1
G0S2 G0/G1 switch 2
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GOLM1 golgi membrane protein 1
HOXC6 homeobox C6
PDE4DIP phosphodiesterase 4D interacting protein
PLAC8 placenta-specific 8
PROM1 prominin 1
PTGES prostaglandin E synthase
PTMA prothymosin, alpha
PXMP2 peroxisomal membrane protein 2, 22kDa
RPL27A ribosomal protein L27a
RPL37A ribosomal protein L37a
RPS11 ribosomal protein S11
SCRG1 stimulator of chondrogenesis 1
SET SET nuclear proto-oncogene
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SRSF6 serine/arginine-rich splicing factor 6
SYNM synemin, intermediate filament protein
TSPAN8 tetraspanin 8