BRD-A13195221_11-(4-Diethylamino-phenyl)-3-phenyl-2,3,4,5,10,11-hexahydro-dibenzo[b,e][1,4]dia_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

51 genes differentially expressed following the BRD-A13195221_11-(4-Diethylamino-phenyl)-3-phenyl-2,3,4,5,10,11-hexahydro-dibenzo[b,e][1,4]dia_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CA2 carbonic anhydrase II
CD36 CD36 molecule (thrombospondin receptor)
CNPY3 canopy FGF signaling regulator 3
CTBP2 C-terminal binding protein 2
DDIT4 DNA-damage-inducible transcript 4
EFNB2 ephrin-B2
FCN1 ficolin (collagen/fibrinogen domain containing) 1
GRN granulin
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
IGL immunoglobulin lambda locus
JUP junction plakoglobin
KIAA1598
KLF5 Kruppel-like factor 5 (intestinal)
LYN LYN proto-oncogene, Src family tyrosine kinase
MEIS2 Meis homeobox 2
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
S100A12 S100 calcium binding protein A12
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
THBS1 thrombospondin 1
TPD52L1 tumor protein D52-like 1
TRIB2 tribbles pseudokinase 2
TSPAN13 tetraspanin 13
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ACOT9 acyl-CoA thioesterase 9
ACTA2 actin, alpha 2, smooth muscle, aorta
ANXA1 annexin A1
ANXA5 annexin A5
CFI complement factor I
CP ceruloplasmin (ferroxidase)
CXCL14 chemokine (C-X-C motif) ligand 14
DCN decorin
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DKK1 dickkopf WNT signaling pathway inhibitor 1
E2F2 E2F transcription factor 2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
HOMER1 homer scaffolding protein 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFI27 interferon, alpha-inducible protein 27
MSX1 msh homeobox 1
PEBP1 phosphatidylethanolamine binding protein 1
PTN pleiotrophin
RBM34 RNA binding motif protein 34
RBP4 retinol binding protein 4, plasma
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
RPS27L ribosomal protein S27-like
S100A2 S100 calcium binding protein A2
SFN stratifin
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)