BRD-A13133631_FLUOROMETHOLONE_A549_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

116 genes differentially expressed following the BRD-A13133631_FLUOROMETHOLONE_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL1 acyl-CoA synthetase long-chain family member 1
AMD1 adenosylmethionine decarboxylase 1
ANO1 anoctamin 1, calcium activated chloride channel
AQP1 aquaporin 1 (Colton blood group)
ARG1 arginase 1
BTBD3 BTB (POZ) domain containing 3
CALD1 caldesmon 1
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
CPM carboxypeptidase M
CRISP3 cysteine-rich secretory protein 3
DUSP1 dual specificity phosphatase 1
E2F2 E2F transcription factor 2
FKBP5 FK506 binding protein 5
FOLR1 folate receptor 1 (adult)
FOXO1 forkhead box O1
GBP1 guanylate binding protein 1, interferon-inducible
GLUL glutamate-ammonia ligase
HBB hemoglobin, beta
HLA-E major histocompatibility complex, class I, E
HOXB2 homeobox B2
IL1R1 interleukin 1 receptor, type I
IRS2 insulin receptor substrate 2
ITM2A integral membrane protein 2A
KLF2 Kruppel-like factor 2
KLK10 kallikrein-related peptidase 10
KRT14 keratin 14, type I
KRT17 keratin 17, type I
KRT5 keratin 5, type II
LCN2 lipocalin 2
LOX lysyl oxidase
LTF lactotransferrin
MBP myelin basic protein
MME membrane metallo-endopeptidase
MSMB microseminoprotein, beta-
MSX1 msh homeobox 1
MT1X metallothionein 1X
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
OLFM1 olfactomedin 1
PDZK1 PDZ domain containing 1
PER1 period circadian clock 1
PRKCH protein kinase C, eta
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RGCC regulator of cell cycle
RGS1 regulator of G-protein signaling 1
RGS4 regulator of G-protein signaling 4
RRAGD Ras-related GTP binding D
S100A2 S100 calcium binding protein A2
S100A9 S100 calcium binding protein A9
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SDC2 syndecan 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
STOM stomatin
TACSTD2 tumor-associated calcium signal transducer 2
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TPD52L1 tumor protein D52-like 1
TSC22D3 TSC22 domain family, member 3
TWIST1 twist family bHLH transcription factor 1
TXNIP thioredoxin interacting protein
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ASPH aspartate beta-hydroxylase
C2CD5 C2 calcium-dependent domain containing 5
C6ORF62 chromosome 6 open reading frame 62
CCL2 chemokine (C-C motif) ligand 2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CELF2 CUGBP, Elav-like family member 2
CLU clusterin
CRELD2 cysteine-rich with EGF-like domains 2
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL12 chemokine (C-X-C motif) ligand 12
CYBA cytochrome b-245, alpha polypeptide
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EPN2 epsin 2
FABP4 fatty acid binding protein 4, adipocyte
FKBP11 FK506 binding protein 11, 19 kDa
FOSL1 FOS-like antigen 1
HEBP1 heme binding protein 1
HHEX hematopoietically expressed homeobox
IGFBP3 insulin-like growth factor binding protein 3
IGHD immunoglobulin heavy constant delta
IL6 interleukin 6
KIAA1598
KRT7 keratin 7, type II
KYNU kynureninase
MARCKS myristoylated alanine-rich protein kinase C substrate
MBOAT7 membrane bound O-acyltransferase domain containing 7
MZB1 marginal zone B and B1 cell-specific protein
PAWR PRKC, apoptosis, WT1, regulator
PDE4B phosphodiesterase 4B, cAMP-specific
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLK2 polo-like kinase 2
PLS1 plastin 1
PON2 paraoxonase 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PROM1 prominin 1
RFC5 replication factor C (activator 1) 5, 36.5kDa
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SOX11 SRY (sex determining region Y)-box 11
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TGFBI transforming growth factor, beta-induced, 68kDa
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TLK2 tousled-like kinase 2
TM9SF3 transmembrane 9 superfamily member 3
TMEM5 transmembrane protein 5
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TXNL4B thioredoxin-like 4B
UGDH UDP-glucose 6-dehydrogenase
WSCD1 WSC domain containing 1