BRD-A13133631_FLUOROMETHOLONE_A549_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

115 genes differentially expressed following the BRD-A13133631_FLUOROMETHOLONE_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
ACAA2 acetyl-CoA acyltransferase 2
ACSL1 acyl-CoA synthetase long-chain family member 1
AKR1C2 aldo-keto reductase family 1, member C2
AREG amphiregulin
CCL20 chemokine (C-C motif) ligand 20
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
COL4A5 collagen, type IV, alpha 5
CPM carboxypeptidase M
CSTA cystatin A (stefin A)
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DDIT4 DNA-damage-inducible transcript 4
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
DSP desmoplakin
DUSP1 dual specificity phosphatase 1
FKBP5 FK506 binding protein 5
FLG filaggrin
FN1 fibronectin 1
GADD45B growth arrest and DNA-damage-inducible, beta
GATA3 GATA binding protein 3
GCH1 GTP cyclohydrolase 1
GLRX glutaredoxin (thioltransferase)
GNAS GNAS complex locus
GPM6B glycoprotein M6B
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
KLF6 Kruppel-like factor 6
KRT14 keratin 14, type I
KRT6A keratin 6A, type II
MAOA monoamine oxidase A
MAPT microtubule-associated protein tau
MCL1 myeloid cell leukemia 1
MTSS1 metastasis suppressor 1
MYO1B myosin IB
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
OXA1L oxidase (cytochrome c) assembly 1-like
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDLIM1 PDZ and LIM domain 1
PEG10 paternally expressed 10
PER1 period circadian clock 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCD protein kinase C, delta
PTGES prostaglandin E synthase
RHOBTB3 Rho-related BTB domain containing 3
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SAT1 spermidine/spermine N1-acetyltransferase 1
SDPR serum deprivation response
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLPI secretory leukocyte peptidase inhibitor
STAT1 signal transducer and activator of transcription 1, 91kDa
SYBU syntabulin (syntaxin-interacting)
TSC22D3 TSC22 domain family, member 3
TSKU tsukushi, small leucine rich proteoglycan
TXNIP thioredoxin interacting protein
VAMP8 vesicle-associated membrane protein 8
ZBTB16 zinc finger and BTB domain containing 16
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ATF5 activating transcription factor 5
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
AXL AXL receptor tyrosine kinase
BACE2 beta-site APP-cleaving enzyme 2
CCL2 chemokine (C-C motif) ligand 2
CDC20 cell division cycle 20
CDCA4 cell division cycle associated 4
CLU clusterin
CSRP2 cysteine and glycine-rich protein 2
CXCL14 chemokine (C-X-C motif) ligand 14
DDB2 damage-specific DNA binding protein 2, 48kDa
DUSP4 dual specificity phosphatase 4
EMX2 empty spiracles homeobox 2
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ETV5 ets variant 5
FAM129A family with sequence similarity 129, member A
FOSL1 FOS-like antigen 1
FOXG1 forkhead box G1
FSTL1 follistatin-like 1
GPNMB glycoprotein (transmembrane) nmb
GREM1 gremlin 1, DAN family BMP antagonist
HOPX HOP homeobox
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IGFBP3 insulin-like growth factor binding protein 3
IGFBP7 insulin-like growth factor binding protein 7
MAP7 microtubule-associated protein 7
MCM5 minichromosome maintenance complex component 5
MID1 midline 1
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle
PDE4B phosphodiesterase 4B, cAMP-specific
PMP22 peripheral myelin protein 22
PROM1 prominin 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTN pleiotrophin
RAB31 RAB31, member RAS oncogene family
RAP1GAP RAP1 GTPase activating protein
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
SNAP25 synaptosomal-associated protein, 25kDa
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPARCL1 SPARC-like 1 (hevin)
STK32B serine/threonine kinase 32B
TGFBI transforming growth factor, beta-induced, 68kDa
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM194A transmembrane protein 194A
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TSPAN8 tetraspanin 8
WIF1 WNT inhibitory factor 1