BRD-A13133631_FLUOROMETHOLONE_A375_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

62 genes differentially expressed following the BRD-A13133631_FLUOROMETHOLONE_A375_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AREG amphiregulin
BTBD3 BTB (POZ) domain containing 3
BTG2 BTG family, member 2
CAV1 caveolin 1, caveolae protein, 22kDa
CCND2 cyclin D2
CD24 CD24 molecule
CFD complement factor D (adipsin)
CKB creatine kinase, brain
COL3A1 collagen, type III, alpha 1
CPD carboxypeptidase D
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DMD dystrophin
DSG2 desmoglein 2
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
F13A1 coagulation factor XIII, A1 polypeptide
FZD5 frizzled class receptor 5
GPC1 glypican 1
GPM6B glycoprotein M6B
HOPX HOP homeobox
IGFBP4 insulin-like growth factor binding protein 4
ITM2A integral membrane protein 2A
JADE2 jade family PHD finger 2
KAT6B K(lysine) acetyltransferase 6B
LAMB1 laminin, beta 1
LGALS3 lectin, galactoside-binding, soluble, 3
METTL7A methyltransferase like 7A
MT1E metallothionein 1E
NFIL3 nuclear factor, interleukin 3 regulated
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PEG10 paternally expressed 10
PLA2G16 phospholipase A2, group XVI
RBM47 RNA binding motif protein 47
RGCC regulator of cell cycle
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SFTPB surfactant protein B
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SOBP sine oculis binding protein homolog (Drosophila)
SPARCL1 SPARC-like 1 (hevin)

decreased expression

Symbol Name
ATP2A3 ATPase, Ca++ transporting, ubiquitous
CLU clusterin
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
HBD hemoglobin, delta
HSPA8 heat shock 70kDa protein 8
IGFBP3 insulin-like growth factor binding protein 3
IL7R interleukin 7 receptor
OXTR oxytocin receptor
PAEP progestagen-associated endometrial protein
PLAC8 placenta-specific 8
PLK2 polo-like kinase 2
PRKACB protein kinase, cAMP-dependent, catalytic, beta
RND3 Rho family GTPase 3
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPM1 tropomyosin 1 (alpha)
TRIB2 tribbles pseudokinase 2
TUBB2A tubulin, beta 2A class IIa