BRD-A13122391_16-HYDROXYTRIPTOLIDE_HT29_6.0_h_0.08_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-A13122391_16-HYDROXYTRIPTOLIDE_HT29_6.0_h_0.08_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
ASPN asporin
CALD1 caldesmon 1
CD9 CD9 molecule
COL11A1 collagen, type XI, alpha 1
ERLIN2 ER lipid raft associated 2
GULP1 GULP, engulfment adaptor PTB domain containing 1
HIST1H1C histone cluster 1, H1c
IFITM3 interferon induced transmembrane protein 3
ISYNA1 inositol-3-phosphate synthase 1
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAOA monoamine oxidase A
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PROSC proline synthetase co-transcribed homolog (bacterial)
RPS4Y1 ribosomal protein S4, Y-linked 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit

decreased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ARID4B AT rich interactive domain 4B (RBP1-like)
CCNF cyclin F
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CFD complement factor D (adipsin)
CLK4 CDC-like kinase 4
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP6 dual specificity phosphatase 6
FAM46A family with sequence similarity 46, member A
FGF13 fibroblast growth factor 13
GRWD1 glutamate-rich WD repeat containing 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
INHBB inhibin, beta B
JADE1 jade family PHD finger 1
JMJD6 jumonji domain containing 6
KEAP1 kelch-like ECH-associated protein 1
KRT81 keratin 81, type II
LDLR low density lipoprotein receptor
LTF lactotransferrin
MCL1 myeloid cell leukemia 1
MMP7 matrix metallopeptidase 7
MYC v-myc avian myelocytomatosis viral oncogene homolog
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NRIP1 nuclear receptor interacting protein 1
NUP62 nucleoporin 62kDa
PDE4D phosphodiesterase 4D, cAMP-specific
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLK1 polo-like kinase 1
PLK2 polo-like kinase 2
POLR1D polymerase (RNA) I polypeptide D, 16kDa
RAB20 RAB20, member RAS oncogene family
RGS2 regulator of G-protein signaling 2
RPP38 ribonuclease P/MRP 38kDa subunit
SOX4 SRY (sex determining region Y)-box 4
SPRY2 sprouty homolog 2 (Drosophila)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TKT transketolase
TOB2 transducer of ERBB2, 2