BRD-A13122391_16-HYDROXYTRIPTOLIDE_AGS_6.0_h_0.08_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

203 genes differentially expressed following the BRD-A13122391_16-HYDROXYTRIPTOLIDE_AGS_6.0_h_0.08_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTN1 actinin, alpha 1
ADD3 adducin 3 (gamma)
AGA aspartylglucosaminidase
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANKRD11 ankyrin repeat domain 11
APLP2 amyloid beta (A4) precursor-like protein 2
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
ASPN asporin
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
BCHE butyrylcholinesterase
BEX4 brain expressed, X-linked 4
BSG basigin (Ok blood group)
C10ORF10 chromosome 10 open reading frame 10
CD44 CD44 molecule (Indian blood group)
CD93 CD93 molecule
CETN2 centrin, EF-hand protein, 2
CFB complement factor B
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLDN10 claudin 10
CLGN calmegin
COL11A1 collagen, type XI, alpha 1
COL1A2 collagen, type I, alpha 2
COL6A1 collagen, type VI, alpha 1
CPD carboxypeptidase D
CPE carboxypeptidase E
CSRP2 cysteine and glycine-rich protein 2
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DAD1 defender against cell death 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EHF ets homologous factor
ERLIN2 ER lipid raft associated 2
FOXN3 forkhead box N3
FZD6 frizzled class receptor 6
GIMAP4 GTPase, IMAP family member 4
GLG1 golgi glycoprotein 1
H2AFY H2A histone family, member Y
HIST1H4C histone cluster 1, H4c
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
KDM4B lysine (K)-specific demethylase 4B
LIMA1 LIM domain and actin binding 1
LRRC15 leucine rich repeat containing 15
MAOA monoamine oxidase A
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYOF myoferlin
NT5E 5'-nucleotidase, ecto (CD73)
PALLD palladin, cytoskeletal associated protein
PBX3 pre-B-cell leukemia homeobox 3
PECAM1 platelet/endothelial cell adhesion molecule 1
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PROSC proline synthetase co-transcribed homolog (bacterial)
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
RAB21 RAB21, member RAS oncogene family
RBP1 retinol binding protein 1, cellular
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPS4Y1 ribosomal protein S4, Y-linked 1
RRAGD Ras-related GTP binding D
RTN1 reticulon 1
SATB1 SATB homeobox 1
SCG2 secretogranin II
SCRN1 secernin 1
SEPT2 septin 2
STK39 serine threonine kinase 39
SULF1 sulfatase 1
SYBU syntabulin (syntaxin-interacting)
TCTN1 tectonic family member 1
THBS2 thrombospondin 2
TLR4 toll-like receptor 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
TPP1 tripeptidyl peptidase I
TRAPPC6A trafficking protein particle complex 6A
TRIB2 tribbles pseudokinase 2
TSPAN7 tetraspanin 7
TTC3 tetratricopeptide repeat domain 3
TULP3 tubby like protein 3
UBE3B ubiquitin protein ligase E3B
UBXN4 UBX domain protein 4
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZFPM2 zinc finger protein, FOG family member 2
ZNF131 zinc finger protein 131

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AREG amphiregulin
AXIN1 axin 1
BAMBI BMP and activin membrane-bound inhibitor
BCL3 B-cell CLL/lymphoma 3
C8ORF4 chromosome 8 open reading frame 4
CALB1 calbindin 1, 28kDa
CCNA2 cyclin A2
CD24 CD24 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CXCL14 chemokine (C-X-C motif) ligand 14
DAPK1 death-associated protein kinase 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLK1 delta-like 1 homolog (Drosophila)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DSG3 desmoglein 3
DUSP4 dual specificity phosphatase 4
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENSA endosulfine alpha
ERBB2 erb-b2 receptor tyrosine kinase 2
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FADS1 fatty acid desaturase 1
FASTKD5 FAST kinase domains 5
FBL fibrillarin
FERMT2 fermitin family member 2
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FOLR1 folate receptor 1 (adult)
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRB14 growth factor receptor-bound protein 14
GRWD1 glutamate-rich WD repeat containing 1
GUSBP11 glucuronidase, beta pseudogene 11
HES1 hes family bHLH transcription factor 1
HMOX1 heme oxygenase 1
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HOPX HOP homeobox
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGFBP4 insulin-like growth factor binding protein 4
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV3-20 immunoglobulin kappa variable 3-20
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IGLV1-40 immunoglobulin lambda variable 1-40
IGLV2-23 immunoglobulin lambda variable 2-23
IGLV3-19 immunoglobulin lambda variable 3-19
INHBB inhibin, beta B
JCHAIN joining chain of multimeric IgA and IgM
JMJD6 jumonji domain containing 6
KANK1 KN motif and ankyrin repeat domains 1
KIAA0125 KIAA0125
KLF10 Kruppel-like factor 10
KRT14 keratin 14, type I
KRT7 keratin 7, type II
LDHB lactate dehydrogenase B
LDLR low density lipoprotein receptor
LTF lactotransferrin
MALL mal, T-cell differentiation protein-like
MARCKS myristoylated alanine-rich protein kinase C substrate
MAT2A methionine adenosyltransferase II, alpha
MCL1 myeloid cell leukemia 1
MIR22HG MIR22 host gene
MSH6 mutS homolog 6
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NPR3 natriuretic peptide receptor 3
ODC1 ornithine decarboxylase 1
PAX5 paired box 5
PLAGL2 pleiomorphic adenoma gene-like 2
PLK1 polo-like kinase 1
POLR1D polymerase (RNA) I polypeptide D, 16kDa
POU2AF1 POU class 2 associating factor 1
PPAP2B phosphatidic acid phosphatase type 2B
PROM1 prominin 1
RANBP6 RAN binding protein 6
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RND3 Rho family GTPase 3
RPP38 ribonuclease P/MRP 38kDa subunit
RPS11 ribosomal protein S11
SCGB2A2 secretoglobin, family 2A, member 2
SGK1 serum/glucocorticoid regulated kinase 1
SIK1 salt-inducible kinase 1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SMAD7 SMAD family member 7
SOCS2 suppressor of cytokine signaling 2
SOX4 SRY (sex determining region Y)-box 4
TACSTD2 tumor-associated calcium signal transducer 2
TESC tescalcin
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TMEM243 transmembrane protein 243, mitochondrial
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNS3 tensin 3
TRIB1 tribbles pseudokinase 1
TSC22D2 TSC22 domain family, member 2
TXLNA taxilin alpha
UBE2S ubiquitin-conjugating enzyme E2S
WIF1 WNT inhibitory factor 1
XBP1 X-box binding protein 1
XIST X inactive specific transcript (non-protein coding)
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZFP36 ZFP36 ring finger protein
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF586 zinc finger protein 586