BRD-A13084692_troglitazone_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

50 genes differentially expressed following the BRD-A13084692_troglitazone_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
BTG2 BTG family, member 2
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DICER1 dicer 1, ribonuclease type III
FOLR1 folate receptor 1 (adult)
IL1B interleukin 1, beta
JUN jun proto-oncogene
MME membrane metallo-endopeptidase
MSLN mesothelin
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH10 myosin, heavy chain 10, non-muscle
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRKCD protein kinase C, delta
SCUBE2 signal peptide, CUB domain, EGF-like 2
TMEM97 transmembrane protein 97
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
ANXA2 annexin A2
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ATF5 activating transcription factor 5
BHLHE40 basic helix-loop-helix family, member e40
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CD24 CD24 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
DFNA5 deafness, autosomal dominant 5
EGFR epidermal growth factor receptor
FAM129A family with sequence similarity 129, member A
HIST1H2BD histone cluster 1, H2bd
HOPX HOP homeobox
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
LTF lactotransferrin
LYPD1 LY6/PLAUR domain containing 1
PEG10 paternally expressed 10
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RBP1 retinol binding protein 1, cellular
RNF167 ring finger protein 167
S100A10 S100 calcium binding protein A10
SCAND1 SCAN domain containing 1
SNX10 sorting nexin 10
SOX9 SRY (sex determining region Y)-box 9
TCERG1 transcription elongation regulator 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TM4SF1 transmembrane 4 L six family member 1
TMEM176B transmembrane protein 176B
TRIB2 tribbles pseudokinase 2
TSPAN8 tetraspanin 8
ZIC1 Zic family member 1