BRD-A13084692_troglitazone_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-A13084692_troglitazone_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASPN asporin
ATF3 activating transcription factor 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLCA4 chloride channel accessory 4
COL10A1 collagen, type X, alpha 1
COL14A1 collagen, type XIV, alpha 1
CRABP2 cellular retinoic acid binding protein 2
CSTA cystatin A (stefin A)
CTAG2 cancer/testis antigen 2
CXADR coxsackie virus and adenovirus receptor
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DSG3 desmoglein 3
HMOX1 heme oxygenase 1
IGL immunoglobulin lambda locus
IL1B interleukin 1, beta
IL1R2 interleukin 1 receptor, type II
IL1RN interleukin 1 receptor antagonist
ITGB5 integrin, beta 5
JUN jun proto-oncogene
KRT13 keratin 13, type I
KRT6A keratin 6A, type II
LY6D lymphocyte antigen 6 complex, locus D
LYZ lysozyme
MMP11 matrix metallopeptidase 11
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
PRKCD protein kinase C, delta
REG1A regenerating islet-derived 1 alpha
REG1B regenerating islet-derived 1 beta
S100A8 S100 calcium binding protein A8
SERINC5 serine incorporator 5
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFN stratifin
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
SPRR3 small proline-rich protein 3

decreased expression

Symbol Name
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP4 dual specificity phosphatase 4
HIST1H2BD histone cluster 1, H2bd
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IRS2 insulin receptor substrate 2
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
PDGFC platelet derived growth factor C
POSTN periostin, osteoblast specific factor
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
SFTPB surfactant protein B
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1