BRD-A13084692_troglitazone_HT115_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

147 genes differentially expressed following the BRD-A13084692_troglitazone_HT115_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ADM adrenomedullin
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANXA1 annexin A1
AQP1 aquaporin 1 (Colton blood group)
ARID1A AT rich interactive domain 1A (SWI-like)
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
BTG1 B-cell translocation gene 1, anti-proliferative
C1S complement component 1, s subcomponent
C3 complement component 3
CCL19 chemokine (C-C motif) ligand 19
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CD164 CD164 molecule, sialomucin
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CPB1 carboxypeptidase B1 (tissue)
CRISP3 cysteine-rich secretory protein 3
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR4 chemokine (C-X-C motif) receptor 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ELANE elastase, neutrophil expressed
FABP6 fatty acid binding protein 6, ileal
FBN1 fibrillin 1
FBXO11 F-box protein 11
FHL1 four and a half LIM domains 1
FOLR1 folate receptor 1 (adult)
GALC galactosylceramidase
GBAS glioblastoma amplified sequence
GSTA1 glutathione S-transferase alpha 1
GSTM3 glutathione S-transferase mu 3 (brain)
GYPC glycophorin C (Gerbich blood group)
HIPK1 homeodomain interacting protein kinase 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
IFITM1 interferon induced transmembrane protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP7 insulin-like growth factor binding protein 7
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IQCG IQ motif containing G
ITGA6 integrin, alpha 6
JAG1 jagged 1
JCHAIN joining chain of multimeric IgA and IgM
KDM5D lysine (K)-specific demethylase 5D
KLF5 Kruppel-like factor 5 (intestinal)
KLHL21 kelch-like family member 21
LAPTM4B lysosomal protein transmembrane 4 beta
LTF lactotransferrin
LXN latexin
MAGEA3 melanoma antigen family A3
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MPO myeloperoxidase
MSMB microseminoprotein, beta-
MSRA methionine sulfoxide reductase A
MTCL1 microtubule crosslinking factor 1
NEB nebulin
NFE2L1 nuclear factor, erythroid 2-like 1
NOV nephroblastoma overexpressed
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PIP prolactin-induced protein
PIR pirin (iron-binding nuclear protein)
PNN pinin, desmosome associated protein
PRAME preferentially expressed antigen in melanoma
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RPS4Y1 ribosomal protein S4, Y-linked 1
SEC14L1 SEC14-like 1 (S. cerevisiae)
SEC63 SEC63 homolog (S. cerevisiae)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SGK1 serum/glucocorticoid regulated kinase 1
SNX11 sorting nexin 11
SRGN serglycin
TIMP1 TIMP metallopeptidase inhibitor 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRIM22 tripartite motif containing 22
TSC22D1 TSC22 domain family, member 1
TSPYL5 TSPY-like 5
TXNIP thioredoxin interacting protein
ZNF512B zinc finger protein 512B

decreased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AMOTL2 angiomotin like 2
ARF3 ADP-ribosylation factor 3
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ASS1 argininosuccinate synthase 1
ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
BID BH3 interacting domain death agonist
C1ORF106 chromosome 1 open reading frame 106
CANT1 calcium activated nucleotidase 1
CCL20 chemokine (C-C motif) ligand 20
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CLDN3 claudin 3
CLDN4 claudin 4
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
CRABP2 cellular retinoic acid binding protein 2
CRIP1 cysteine-rich protein 1 (intestinal)
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CXCL5 chemokine (C-X-C motif) ligand 5
CYR61 cysteine-rich, angiogenic inducer, 61
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
FBP1 fructose-1,6-bisphosphatase 1
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
GHITM growth hormone inducible transmembrane protein
GNAS GNAS complex locus
HEATR1 HEAT repeat containing 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HNMT histamine N-methyltransferase
KIAA0226L KIAA0226-like
KIAA1033 KIAA1033
KRT7 keratin 7, type II
LITAF lipopolysaccharide-induced TNF factor
LMO3 LIM domain only 3 (rhombotin-like 2)
LPCAT1 lysophosphatidylcholine acyltransferase 1
LTB lymphotoxin beta (TNF superfamily, member 3)
LY6E lymphocyte antigen 6 complex, locus E
MDFIC MyoD family inhibitor domain containing
MRPS16 mitochondrial ribosomal protein S16
MX2 MX dynamin-like GTPase 2
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFIB nuclear factor I/B
NPC2 Niemann-Pick disease, type C2
PDZRN3 PDZ domain containing ring finger 3
PGAM1 phosphoglycerate mutase 1 (brain)
PI3 peptidase inhibitor 3, skin-derived
PTEN phosphatase and tensin homolog
PTPRK protein tyrosine phosphatase, receptor type, K
PUF60 poly-U binding splicing factor 60KDa
RAB25 RAB25, member RAS oncogene family
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RBM47 RNA binding motif protein 47
RGS10 regulator of G-protein signaling 10
RGS2 regulator of G-protein signaling 2
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
SAMD4A sterile alpha motif domain containing 4A
SPINK1 serine peptidase inhibitor, Kazal type 1
TES testin LIM domain protein
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast)
TMSB15A thymosin beta 15a
XIST X inactive specific transcript (non-protein coding)