BRD-A13021932_BMS509744_HEPG2_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

58 genes differentially expressed following the BRD-A13021932_BMS509744_HEPG2_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ACAA1 acetyl-CoA acyltransferase 1
ADGRG2 adhesion G protein-coupled receptor G2
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
AQP3 aquaporin 3 (Gill blood group)
BTN3A2 butyrophilin, subfamily 3, member A2
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CST1 cystatin SN
EML3 echinoderm microtubule associated protein like 3
EMX2 empty spiracles homeobox 2
FADS1 fatty acid desaturase 1
FAM63A family with sequence similarity 63, member A
LAMP5 lysosomal-associated membrane protein family, member 5
LDHB lactate dehydrogenase B
LPAR1 lysophosphatidic acid receptor 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NNT nicotinamide nucleotide transhydrogenase
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PRKD3 protein kinase D3
RGS2 regulator of G-protein signaling 2
RHOBTB3 Rho-related BTB domain containing 3
SC5D sterol-C5-desaturase
SGCE sarcoglycan, epsilon
SGK1 serum/glucocorticoid regulated kinase 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10

decreased expression

Symbol Name
ALOX5 arachidonate 5-lipoxygenase
AMIGO2 adhesion molecule with Ig-like domain 2
CA2 carbonic anhydrase II
CAV1 caveolin 1, caveolae protein, 22kDa
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
EPAS1 endothelial PAS domain protein 1
FLT1 fms-related tyrosine kinase 1
GPNMB glycoprotein (transmembrane) nmb
IGL immunoglobulin lambda locus
JCHAIN joining chain of multimeric IgA and IgM
LOXL2 lysyl oxidase-like 2
LYZ lysozyme
MATN2 matrilin 2
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NES nestin
NOTCH3 notch 3
PAPD7 PAP associated domain containing 7
PHLDA1 pleckstrin homology-like domain, family A, member 1
RGCC regulator of cell cycle
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SDC4 syndecan 4
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
TPM1 tropomyosin 1 (alpha)
TSPAN7 tetraspanin 7
VDAC1 voltage-dependent anion channel 1
WNT5A wingless-type MMTV integration site family, member 5A
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZNF706 zinc finger protein 706