BRD-A13021932_BMS509744_HA1E_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

129 genes differentially expressed following the BRD-A13021932_BMS509744_HA1E_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD9 CD9 molecule
CHEK2 checkpoint kinase 2
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
ECM1 extracellular matrix protein 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ETV1 ets variant 1
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDPS farnesyl diphosphate synthase
GLRX glutaredoxin (thioltransferase)
HDAC6 histone deacetylase 6
HIST1H2BK histone cluster 1, H2bk
HLA-C major histocompatibility complex, class I, C
HMGB3 high mobility group box 3
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
IQGAP1 IQ motif containing GTPase activating protein 1
KDM5D lysine (K)-specific demethylase 5D
LDLR low density lipoprotein receptor
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LOC100272216 uncharacterized LOC100272216
MBOAT7 membrane bound O-acyltransferase domain containing 7
MOXD1 monooxygenase, DBH-like 1
MSMO1 methylsterol monooxygenase 1
NELL2 NEL-like 2 (chicken)
NR1D2 nuclear receptor subfamily 1, group D, member 2
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
NSDHL NAD(P) dependent steroid dehydrogenase-like
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PAMR1 peptidase domain containing associated with muscle regeneration 1
PIGP phosphatidylinositol glycan anchor biosynthesis, class P
PSD3 pleckstrin and Sec7 domain containing 3
RGS2 regulator of G-protein signaling 2
RPS4Y1 ribosomal protein S4, Y-linked 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SPP1 secreted phosphoprotein 1
SPRY2 sprouty homolog 2 (Drosophila)
SQLE squalene epoxidase
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STC1 stanniocalcin 1
TGIF1 TGFB-induced factor homeobox 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TM7SF2 transmembrane 7 superfamily member 2
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRIM2 tripartite motif containing 2
WDTC1 WD and tetratricopeptide repeats 1
XPO7 exportin 7

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
ADA adenosine deaminase
AIF1 allograft inflammatory factor 1
AK4 adenylate kinase 4
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
BZW2 basic leucine zipper and W2 domains 2
C1QA complement component 1, q subcomponent, A chain
CA12 carbonic anhydrase XII
CADM1 cell adhesion molecule 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC92 coiled-coil domain containing 92
CCL19 chemokine (C-C motif) ligand 19
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CCNA2 cyclin A2
CENPU centromere protein U
CLEC2B C-type lectin domain family 2, member B
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CST7 cystatin F (leukocystatin)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL9 chemokine (C-X-C motif) ligand 9
DLK1 delta-like 1 homolog (Drosophila)
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DPYSL3 dihydropyrimidinase-like 3
EDN1 endothelin 1
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
F13A1 coagulation factor XIII, A1 polypeptide
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FGFR2 fibroblast growth factor receptor 2
GAL galanin/GMAP prepropeptide
GBP1 guanylate binding protein 1, interferon-inducible
GLIPR1 GLI pathogenesis-related 1
GNAS GNAS complex locus
IGFBP3 insulin-like growth factor binding protein 3
IGFBP4 insulin-like growth factor binding protein 4
IGFBP5 insulin-like growth factor binding protein 5
IL32 interleukin 32
ITK IL2-inducible T-cell kinase
JCHAIN joining chain of multimeric IgA and IgM
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRT7 keratin 7, type II
LCN2 lipocalin 2
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
MARCKS myristoylated alanine-rich protein kinase C substrate
MFAP5 microfibrillar associated protein 5
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MYO5A myosin VA (heavy chain 12, myoxin)
NLRP2 NLR family, pyrin domain containing 2
PADI2 peptidyl arginine deiminase, type II
PALLD palladin, cytoskeletal associated protein
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PRDX4 peroxiredoxin 4
PTGDS prostaglandin D2 synthase 21kDa (brain)
PYCR1 pyrroline-5-carboxylate reductase 1
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RHOB ras homolog family member B
RRM2 ribonucleotide reductase M2
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RTN1 reticulon 1
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC35F2 solute carrier family 35, member F2
TPM1 tropomyosin 1 (alpha)
TRAF3IP3 TRAF3 interacting protein 3
TRBC1 T cell receptor beta constant 1
TTC39A tetratricopeptide repeat domain 39A
VWF von Willebrand factor