BRD-A12409803_-666_VCAP_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-A12409803_-666_VCAP_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA1 annexin A1
ARMCX1 armadillo repeat containing, X-linked 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CAST calpastatin
CD36 CD36 molecule (thrombospondin receptor)
CDO1 cysteine dioxygenase type 1
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FOXO3 forkhead box O3
GLRX glutaredoxin (thioltransferase)
GLUL glutamate-ammonia ligase
GOLGA8H golgin A8 family, member H
LGMN legumain
PBX3 pre-B-cell leukemia homeobox 3
PEG3 paternally expressed 3
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RHOBTB3 Rho-related BTB domain containing 3
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPL37A ribosomal protein L37a
RYBP RING1 and YY1 binding protein
S100A8 S100 calcium binding protein A8
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SFRP4 secreted frizzled-related protein 4
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SNAI2 snail family zinc finger 2
SOD2 superoxide dismutase 2, mitochondrial
TBC1D5 TBC1 domain family, member 5
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM176B transmembrane protein 176B

decreased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADGRE5 adhesion G protein-coupled receptor E5
CA12 carbonic anhydrase XII
CCL19 chemokine (C-C motif) ligand 19
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CXCL14 chemokine (C-X-C motif) ligand 14
EPCAM epithelial cell adhesion molecule
GDF15 growth differentiation factor 15
HOPX HOP homeobox
IGFBP3 insulin-like growth factor binding protein 3
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
JADE2 jade family PHD finger 2
LOXL1 lysyl oxidase-like 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
PRSS21 protease, serine, 21 (testisin)
RAP1GAP RAP1 GTPase activating protein
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SFTPC surfactant protein C
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC35F2 solute carrier family 35, member F2
TRIB1 tribbles pseudokinase 1
TSPAN8 tetraspanin 8
UQCRH ubiquinol-cytochrome c reductase hinge protein