BRD-A12230535_Nutlin-3_HT29_6.0_h_44.4_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

27 genes differentially expressed following the BRD-A12230535_Nutlin-3_HT29_6.0_h_44.4_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
BAG3 BCL2-associated athanogene 3
C6ORF48 chromosome 6 open reading frame 48
COL15A1 collagen, type XV, alpha 1
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10
F3 coagulation factor III (thromboplastin, tissue factor)
FOXO3 forkhead box O3
GARS glycyl-tRNA synthetase
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GLRX glutaredoxin (thioltransferase)
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
IGFBP5 insulin-like growth factor binding protein 5
IL6ST interleukin 6 signal transducer
MUC5B mucin 5B, oligomeric mucus/gel-forming
NUPR1 nuclear protein, transcriptional regulator, 1
PDIA4 protein disulfide isomerase family A, member 4
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
SFRP4 secreted frizzled-related protein 4
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
CCNF cyclin F
CXADR coxsackie virus and adenovirus receptor
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
TM4SF1 transmembrane 4 L six family member 1