BRD-A11990600_lorazepam_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

32 genes differentially expressed following the BRD-A11990600_lorazepam_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANKRD10 ankyrin repeat domain 10
CALD1 caldesmon 1
CTSL cathepsin L
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
EGR3 early growth response 3
EPRS glutamyl-prolyl-tRNA synthetase
KIAA0485 uncharacterized LOC57235
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPT microtubule-associated protein tau
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NFIB nuclear factor I/B
OXCT1 3-oxoacid CoA transferase 1
PLA2G16 phospholipase A2, group XVI
RRP1B ribosomal RNA processing 1B
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF1 trefoil factor 1
TLR4 toll-like receptor 4
TSPAN8 tetraspanin 8

decreased expression

Symbol Name
CADM1 cell adhesion molecule 1
CD52 CD52 molecule
FST follistatin
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IL7R interleukin 7 receptor
INSIG1 insulin induced gene 1
KRT19 keratin 19, type I
RBP1 retinol binding protein 1, cellular
S100A9 S100 calcium binding protein A9
TPSAB1 tryptase alpha/beta 1
XIST X inactive specific transcript (non-protein coding)