BRD-A11929187_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

102 genes differentially expressed following the BRD-A11929187_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BTBD3 BTB (POZ) domain containing 3
CA2 carbonic anhydrase II
CD24 CD24 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLDN3 claudin 3
CLGN calmegin
CPA3 carboxypeptidase A3 (mast cell)
DACH1 dachshund family transcription factor 1
DCN decorin
DENND1B DENN/MADD domain containing 1B
EGLN3 egl-9 family hypoxia-inducible factor 3
EPN2 epsin 2
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IPO13 importin 13
ISOC1 isochorismatase domain containing 1
JAG1 jagged 1
JCHAIN joining chain of multimeric IgA and IgM
KIAA0226L KIAA0226-like
KRT23 keratin 23, type I
LDOC1 leucine zipper, down-regulated in cancer 1
LMO3 LIM domain only 3 (rhombotin-like 2)
LUM lumican
MME membrane metallo-endopeptidase
MMP2 matrix metallopeptidase 2
MSMB microseminoprotein, beta-
MTSS1 metastasis suppressor 1
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NPTX2 neuronal pentraxin II
OSBPL10 oxysterol binding protein-like 10
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PELI1 pellino E3 ubiquitin protein ligase 1
PLIN2 perilipin 2
PPOX protoporphyrinogen oxidase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTN pleiotrophin
RGCC regulator of cell cycle
RGS5 regulator of G-protein signaling 5
SCGB2A1 secretoglobin, family 2A, member 1
SDC1 syndecan 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SHB Src homology 2 domain containing adaptor protein B
SLC38A1 solute carrier family 38, member 1
SMAD1 SMAD family member 1
SORBS1 sorbin and SH3 domain containing 1
SOX11 SRY (sex determining region Y)-box 11
TACC2 transforming, acidic coiled-coil containing protein 2
TCF4 transcription factor 4
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TPPP3 tubulin polymerization-promoting protein family member 3
TRIB3 tribbles pseudokinase 3
VEGFA vascular endothelial growth factor A
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ANXA6 annexin A6
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
BID BH3 interacting domain death agonist
C8ORF4 chromosome 8 open reading frame 4
CD99 CD99 molecule
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CXCL8 chemokine (C-X-C motif) ligand 8
DAPK1 death-associated protein kinase 1
EMP3 epithelial membrane protein 3
FLNA filamin A, alpha
FOLR1 folate receptor 1 (adult)
GOLM1 golgi membrane protein 1
HOXA5 homeobox A5
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KRT7 keratin 7, type II
LAMB1 laminin, beta 1
NID2 nidogen 2 (osteonidogen)
PAN2 PAN2 poly(A) specific ribonuclease subunit
PLAGL1 pleiomorphic adenoma gene-like 1
PROM1 prominin 1
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RAD23B RAD23 homolog B (S. cerevisiae)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RCN1 reticulocalbin 1, EF-hand calcium binding domain
REEP5 receptor accessory protein 5
RNF167 ring finger protein 167
RPL27A ribosomal protein L27a
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
SKAP2 src kinase associated phosphoprotein 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SRSF6 serine/arginine-rich splicing factor 6
STXBP2 syntaxin binding protein 2
TBC1D4 TBC1 domain family, member 4
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFBI transforming growth factor, beta-induced, 68kDa
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
VCAN versican