BRD-A11706664_EI-332_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-A11706664_EI-332_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ATF4 activating transcription factor 4
CLCN3 chloride channel, voltage-sensitive 3
CST3 cystatin C
DAPK1 death-associated protein kinase 1
DDIT4 DNA-damage-inducible transcript 4
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
HEATR1 HEAT repeat containing 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IPW imprinted in Prader-Willi syndrome (non-protein coding)
IRS2 insulin receptor substrate 2
KDM7A lysine (K)-specific demethylase 7A
MT1M metallothionein 1M
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PCSK5 proprotein convertase subtilisin/kexin type 5
PPAP2B phosphatidic acid phosphatase type 2B
PRSS8 protease, serine, 8
RGS2 regulator of G-protein signaling 2
SIAH2 siah E3 ubiquitin protein ligase 2
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
STC2 stanniocalcin 2
TARS threonyl-tRNA synthetase
TIMP3 TIMP metallopeptidase inhibitor 3

decreased expression

Symbol Name
CDC25A cell division cycle 25A
CDC7 cell division cycle 7
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
HBB hemoglobin, beta
IFI16 interferon, gamma-inducible protein 16
IGFBP7 insulin-like growth factor binding protein 7
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
KIF14 kinesin family member 14
MAN1A1 mannosidase, alpha, class 1A, member 1
MEG3 maternally expressed 3 (non-protein coding)
MXRA7 matrix-remodelling associated 7
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NID1 nidogen 1
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
RRAGD Ras-related GTP binding D
S100A13 S100 calcium binding protein A13
STC1 stanniocalcin 1
WT1 Wilms tumor 1