BRD-A11706664_EI-332_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

115 genes differentially expressed following the BRD-A11706664_EI-332_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
CADM1 cell adhesion molecule 1
CHGB chromogranin B
CLC Charcot-Leyden crystal galectin
COL11A1 collagen, type XI, alpha 1
COL1A1 collagen, type I, alpha 1
DCN decorin
ERAP1 endoplasmic reticulum aminopeptidase 1
FGFR2 fibroblast growth factor receptor 2
GAS6 growth arrest-specific 6
GPNMB glycoprotein (transmembrane) nmb
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IFITM1 interferon induced transmembrane protein 1
IL13RA1 interleukin 13 receptor, alpha 1
INSM1 insulinoma-associated 1
ISYNA1 inositol-3-phosphate synthase 1
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAOA monoamine oxidase A
MT1E metallothionein 1E
MT1M metallothionein 1M
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGS5 regulator of G-protein signaling 5
RNASE6 ribonuclease, RNase A family, k6
RTN1 reticulon 1
SDC2 syndecan 2
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SOCS2 suppressor of cytokine signaling 2
TGFBI transforming growth factor, beta-induced, 68kDa
TMSB15A thymosin beta 15a
TSPAN7 tetraspanin 7
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

decreased expression

Symbol Name
ACBD3 acyl-CoA binding domain containing 3
ACSL1 acyl-CoA synthetase long-chain family member 1
AHNAK2 AHNAK nucleoprotein 2
AIM1 absent in melanoma 1
AQP3 aquaporin 3 (Gill blood group)
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
AURKA aurora kinase A
C1ORF106 chromosome 1 open reading frame 106
CALML5 calmodulin-like 5
CANT1 calcium activated nucleotidase 1
CBR3 carbonyl reductase 3
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHERP calcium homeostasis endoplasmic reticulum protein
CLCA2 chloride channel accessory 2
CLTC clathrin, heavy chain (Hc)
CXCL6 chemokine (C-X-C motif) ligand 6
DEFB1 defensin, beta 1
DEGS1 delta(4)-desaturase, sphingolipid 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
EHD1 EH-domain containing 1
EIF5 eukaryotic translation initiation factor 5
ETV1 ets variant 1
FASTKD5 FAST kinase domains 5
FLNA filamin A, alpha
FOSL1 FOS-like antigen 1
FOXJ3 forkhead box J3
GCH1 GTP cyclohydrolase 1
HOPX HOP homeobox
IGFBP4 insulin-like growth factor binding protein 4
JMJD6 jumonji domain containing 6
KDM2A lysine (K)-specific demethylase 2A
KRT10 keratin 10, type I
KRT14 keratin 14, type I
KRT17 keratin 17, type I
KRT7 keratin 7, type II
MAGED1 melanoma antigen family D1
MED1 mediator complex subunit 1
MKNK2 MAP kinase interacting serine/threonine kinase 2
MLPH melanophilin
MTF2 metal response element binding transcription factor 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NRIP1 nuclear receptor interacting protein 1
NUP62 nucleoporin 62kDa
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RGS2 regulator of G-protein signaling 2
RPL36AL ribosomal protein L36a-like
RPP38 ribonuclease P/MRP 38kDa subunit
S100A2 S100 calcium binding protein A2
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SETD5 SET domain containing 5
SFN stratifin
SIX1 SIX homeobox 1
SLPI secretory leukocyte peptidase inhibitor
SMAD3 SMAD family member 3
SON SON DNA binding protein
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX4 SRY (sex determining region Y)-box 4
SOX9 SRY (sex determining region Y)-box 9
STX1A syntaxin 1A (brain)
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TACSTD2 tumor-associated calcium signal transducer 2
TFF1 trefoil factor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TM4SF1 transmembrane 4 L six family member 1
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TXLNA taxilin alpha
VCPKMT valosin containing protein lysine (K) methyltransferase
WIPF2 WAS/WASL interacting protein family, member 2
WWTR1 WW domain containing transcription regulator 1
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2
ZNF185 zinc finger protein 185 (LIM domain)