BRD-A11706664_EI-332_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

95 genes differentially expressed following the BRD-A11706664_EI-332_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ACKR3 atypical chemokine receptor 3
ADCK3 aarF domain containing kinase 3
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
BTG1 B-cell translocation gene 1, anti-proliferative
CCNG2 cyclin G2
CDK7 cyclin-dependent kinase 7
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHMP1B charged multivesicular body protein 1B
CXCL8 chemokine (C-X-C motif) ligand 8
DUSP6 dual specificity phosphatase 6
EAPP E2F-associated phosphoprotein
ERBB3 erb-b2 receptor tyrosine kinase 3
FAM60A family with sequence similarity 60, member A
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
HBP1 HMG-box transcription factor 1
HILPDA hypoxia inducible lipid droplet-associated
HMOX1 heme oxygenase 1
IRF2 interferon regulatory factor 2
ITGB6 integrin, beta 6
JUND jun D proto-oncogene
KEAP1 kelch-like ECH-associated protein 1
KYNU kynureninase
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MMP7 matrix metallopeptidase 7
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PNRC1 proline-rich nuclear receptor coactivator 1
PUM2 pumilio RNA-binding family member 2
RFX5 regulatory factor X, 5 (influences HLA class II expression)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMAD3 SMAD family member 3
SOD2 superoxide dismutase 2, mitochondrial
SOX4 SRY (sex determining region Y)-box 4
STAR steroidogenic acute regulatory protein
TGIF1 TGFB-induced factor homeobox 1
TICAM1 toll-like receptor adaptor molecule 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TRIB1 tribbles pseudokinase 1
TRIM16 tripartite motif containing 16
TSKU tsukushi, small leucine rich proteoglycan
TXNRD1 thioredoxin reductase 1
VLDLR very low density lipoprotein receptor
WEE1 WEE1 G2 checkpoint kinase
ZFP36 ZFP36 ring finger protein
ZHX2 zinc fingers and homeoboxes 2

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
BCHE butyrylcholinesterase
C7 complement component 7
CCL13 chemokine (C-C motif) ligand 13
CD209 CD209 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CENPE centromere protein E, 312kDa
CFH complement factor H
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
COL3A1 collagen, type III, alpha 1
CRIP2 cysteine-rich protein 2
CRP C-reactive protein, pentraxin-related
CYBA cytochrome b-245, alpha polypeptide
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7
EBP emopamil binding protein (sterol isomerase)
EFNB2 ephrin-B2
FABP1 fatty acid binding protein 1, liver
GAS6 growth arrest-specific 6
GUK1 guanylate kinase 1
HAL histidine ammonia-lyase
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
IGFBP7 insulin-like growth factor binding protein 7
ISG15 ISG15 ubiquitin-like modifier
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
LGALS4 lectin, galactoside-binding, soluble, 4
MXRA5 matrix-remodelling associated 5
MXRA7 matrix-remodelling associated 7
NUAK1 NUAK family, SNF1-like kinase, 1
ODC1 ornithine decarboxylase 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PXMP2 peroxisomal membrane protein 2, 22kDa
SCG5 secretogranin V
SEPW1 selenoprotein W, 1
SPINT2 serine peptidase inhibitor, Kunitz type, 2
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
THY1 Thy-1 cell surface antigen
TMSB15A thymosin beta 15a
TSPAN4 tetraspanin 4
TSPAN8 tetraspanin 8
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17