BRD-A11706664_EI-332_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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77 genes differentially expressed following the BRD-A11706664_EI-332_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATHL1 ATH1, acid trehalase-like 1 (yeast)
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
CXCL13 chemokine (C-X-C motif) ligand 13
DLX2 distal-less homeobox 2
FABP7 fatty acid binding protein 7, brain
HEBP1 heme binding protein 1
HMOX1 heme oxygenase 1
IL32 interleukin 32
KCTD12 potassium channel tetramerization domain containing 12
KDM5B lysine (K)-specific demethylase 5B
LTF lactotransferrin
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MBNL2 muscleblind-like splicing regulator 2
MCUR1 mitochondrial calcium uniporter regulator 1
MKNK1 MAP kinase interacting serine/threonine kinase 1
MRPS30 mitochondrial ribosomal protein S30
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NUDCD3 NudC domain containing 3
NUP153 nucleoporin 153kDa
OBSL1 obscurin-like 1
PPAP2B phosphatidic acid phosphatase type 2B
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
TNS3 tensin 3
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ADD3 adducin 3 (gamma)
ADI1 acireductone dioxygenase 1
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
C3ORF14 chromosome 3 open reading frame 14
CAST calpastatin
CCND1 cyclin D1
CD200 CD200 molecule
CLTB clathrin, light chain B
COL14A1 collagen, type XIV, alpha 1
COL15A1 collagen, type XV, alpha 1
CPE carboxypeptidase E
CYBA cytochrome b-245, alpha polypeptide
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPP4 dipeptidyl-peptidase 4
EIF5A eukaryotic translation initiation factor 5A
FBN1 fibrillin 1
FGF13 fibroblast growth factor 13
GAA glucosidase, alpha; acid
GOLGA8A golgin A8 family, member A
HEPH hephaestin
IGF1R insulin-like growth factor 1 receptor
IGFBP5 insulin-like growth factor binding protein 5
ISG15 ISG15 ubiquitin-like modifier
ITFG1 integrin alpha FG-GAP repeat containing 1
ITM2A integral membrane protein 2A
KIF14 kinesin family member 14
LY75 lymphocyte antigen 75
MFAP5 microfibrillar associated protein 5
MPDZ multiple PDZ domain protein
NAAA N-acylethanolamine acid amidase
NDN necdin, melanoma antigen (MAGE) family member
NPTX2 neuronal pentraxin II
NT5E 5'-nucleotidase, ecto (CD73)
PBLD phenazine biosynthesis-like protein domain containing
PBX3 pre-B-cell leukemia homeobox 3
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
RAB4A RAB4A, member RAS oncogene family
RGS5 regulator of G-protein signaling 5
RPL39L ribosomal protein L39-like
S100A2 S100 calcium binding protein A2
SFRP1 secreted frizzled-related protein 1
TCTN1 tectonic family member 1
TFF1 trefoil factor 1
THBS2 thrombospondin 2
TMEM47 transmembrane protein 47
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
ZBTB20 zinc finger and BTB domain containing 20