BRD-A11706664_EI-332_ASC_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

102 genes differentially expressed following the BRD-A11706664_EI-332_ASC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ATP9A ATPase, class II, type 9A
BST2 bone marrow stromal cell antigen 2
C2CD2 C2 calcium-dependent domain containing 2
CALD1 caldesmon 1
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CES1 carboxylesterase 1
CSRP1 cysteine and glycine-rich protein 1
CTGF connective tissue growth factor
CTSL cathepsin L
DCN decorin
GAS1 growth arrest-specific 1
GHR growth hormone receptor
GULP1 GULP, engulfment adaptor PTB domain containing 1
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFI6 interferon, alpha-inducible protein 6
IGHM immunoglobulin heavy constant mu
IL1R1 interleukin 1 receptor, type I
IRS1 insulin receptor substrate 1
ISG15 ISG15 ubiquitin-like modifier
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LHFP lipoma HMGIC fusion partner
LYPD1 LY6/PLAUR domain containing 1
MAOA monoamine oxidase A
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MTUS1 microtubule associated tumor suppressor 1
NYNRIN NYN domain and retroviral integrase containing
PALLD palladin, cytoskeletal associated protein
PBX1 pre-B-cell leukemia homeobox 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLCB4 phospholipase C, beta 4
PRKX protein kinase, X-linked
PTGIS prostaglandin I2 (prostacyclin) synthase
PTK2B protein tyrosine kinase 2 beta
RGS16 regulator of G-protein signaling 16
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SQSTM1 sequestosome 1
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
SULF1 sulfatase 1
SYT1 synaptotagmin I
THBS4 thrombospondin 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
WASL Wiskott-Aldrich syndrome-like

decreased expression

Symbol Name
ALDOC aldolase C, fructose-bisphosphate
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
C6ORF62 chromosome 6 open reading frame 62
CA12 carbonic anhydrase XII
CA2 carbonic anhydrase II
CA9 carbonic anhydrase IX
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CCND2 cyclin D2
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CDC20 cell division cycle 20
CSTA cystatin A (stefin A)
CXCL8 chemokine (C-X-C motif) ligand 8
DCK deoxycytidine kinase
DLK1 delta-like 1 homolog (Drosophila)
ENO1 enolase 1, (alpha)
FRZB frizzled-related protein
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
HILPDA hypoxia inducible lipid droplet-associated
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA8 heat shock 70kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRT14 keratin 14, type I
KRT5 keratin 5, type II
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NFIL3 nuclear factor, interleukin 3 regulated
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
PDZK1 PDZ domain containing 1
PELI1 pellino E3 ubiquitin protein ligase 1
PGK1 phosphoglycerate kinase 1
PHGDH phosphoglycerate dehydrogenase
PRDX2 peroxiredoxin 2
PSAT1 phosphoserine aminotransferase 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPAG4 sperm associated antigen 4
SPINK5 serine peptidase inhibitor, Kazal type 5
STC2 stanniocalcin 2
TGFA transforming growth factor, alpha
TMEM45A transmembrane protein 45A
TPD52 tumor protein D52
TUBB2A tubulin, beta 2A class IIa
TYMS thymidylate synthetase
UBE2C ubiquitin-conjugating enzyme E2C
VDAC1 voltage-dependent anion channel 1
VEGFA vascular endothelial growth factor A
YBX1 Y box binding protein 1