BRD-A11702965_230752_SKB_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

154 genes differentially expressed following the BRD-A11702965_230752_SKB_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADAT1 adenosine deaminase, tRNA-specific 1
APOB apolipoprotein B
ARHGAP32 Rho GTPase activating protein 32
CA12 carbonic anhydrase XII
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCL20 chemokine (C-C motif) ligand 20
CES1 carboxylesterase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLIC3 chloride intracellular channel 3
CLU clusterin
COL18A1 collagen, type XVIII, alpha 1
COL6A1 collagen, type VI, alpha 1
CRABP1 cellular retinoic acid binding protein 1
CTSV cathepsin V
CTSZ cathepsin Z
CXCL10 chemokine (C-X-C motif) ligand 10
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
EGFL6 EGF-like-domain, multiple 6
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EML3 echinoderm microtubule associated protein like 3
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FABP6 fatty acid binding protein 6, ileal
FGFR3 fibroblast growth factor receptor 3
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H1C histone cluster 1, H1c
HNRNPL heterogeneous nuclear ribonucleoprotein L
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFITM1 interferon induced transmembrane protein 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL2RG interleukin 2 receptor, gamma
IQGAP1 IQ motif containing GTPase activating protein 1
KRT16 keratin 16, type I
KRT4 keratin 4, type II
LEF1 lymphoid enhancer-binding factor 1
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LTBP1 latent transforming growth factor beta binding protein 1
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MEIS1 Meis homeobox 1
MMP1 matrix metallopeptidase 1
MMP12 matrix metallopeptidase 12
MMP9 matrix metallopeptidase 9
NDRG1 N-myc downstream regulated 1
NTS neurotensin
ORM1 orosomucoid 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PERP PERP, TP53 apoptosis effector
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
RGS5 regulator of G-protein signaling 5
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SCARB2 scavenger receptor class B, member 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SPARCL1 SPARC-like 1 (hevin)
STC1 stanniocalcin 1
TDO2 tryptophan 2,3-dioxygenase
TMSB15A thymosin beta 15a
TWIST1 twist family bHLH transcription factor 1
VSNL1 visinin-like 1
ZBED2 zinc finger, BED-type containing 2

decreased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ADSL adenylosuccinate lyase
AK1 adenylate kinase 1
ANK2 ankyrin 2, neuronal
ANXA3 annexin A3
ANXA6 annexin A6
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOD apolipoprotein D
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARMCX2 armadillo repeat containing, X-linked 2
ATF4 activating transcription factor 4
ATG3 autophagy related 3
BASP1 brain abundant, membrane attached signal protein 1
BIN1 bridging integrator 1
BLCAP bladder cancer associated protein
CDC25B cell division cycle 25B
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDV3 CDV3 homolog (mouse)
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CTBP2 C-terminal binding protein 2
CX3CR1 chemokine (C-X3-C motif) receptor 1
DDIT4 DNA-damage-inducible transcript 4
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DUSP4 dual specificity phosphatase 4
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EIF3F eukaryotic translation initiation factor 3, subunit F
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EIF5A eukaryotic translation initiation factor 5A
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FABP7 fatty acid binding protein 7, brain
FHL2 four and a half LIM domains 2
FOXO3 forkhead box O3
FPGS folylpolyglutamate synthase
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GDF15 growth differentiation factor 15
GDI2 GDP dissociation inhibitor 2
GNAS GNAS complex locus
GPX1 glutathione peroxidase 1
GRSF1 G-rich RNA sequence binding factor 1
GYG1 glycogenin 1
HMOX1 heme oxygenase 1
HN1 hematological and neurological expressed 1
HSPA8 heat shock 70kDa protein 8
KLF4 Kruppel-like factor 4 (gut)
LTF lactotransferrin
MACF1 microtubule-actin crosslinking factor 1
MAGED1 melanoma antigen family D1
MAP1B microtubule-associated protein 1B
MARCKS myristoylated alanine-rich protein kinase C substrate
MYBPC1 myosin binding protein C, slow type
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic
NOP56 NOP56 ribonucleoprotein
NOTCH1 notch 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRN1 neuritin 1
NUP62 nucleoporin 62kDa
NXN nucleoredoxin
PCNA proliferating cell nuclear antigen
POPDC3 popeye domain containing 3
PTX3 pentraxin 3, long
RAE1 ribonucleic acid export 1
RNF114 ring finger protein 114
RNF167 ring finger protein 167
RPL27A ribosomal protein L27a
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
RPS4Y1 ribosomal protein S4, Y-linked 1
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SEPT9 septin 9
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SNRPB2 small nuclear ribonucleoprotein polypeptide B
SNRPE small nuclear ribonucleoprotein polypeptide E
SRPX sushi-repeat containing protein, X-linked
STOM stomatin
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNPO1 transportin 1
TRIM8 tripartite motif containing 8
TSPO translocator protein (18kDa)
TXLNA taxilin alpha
TXNDC9 thioredoxin domain containing 9
UROD uroporphyrinogen decarboxylase
USP22 ubiquitin specific peptidase 22
VCAN versican
WSB2 WD repeat and SOCS box containing 2
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZDHHC7 zinc finger, DHHC-type containing 7