BRD-A11702965_230752_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

71 genes differentially expressed following the BRD-A11702965_230752_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
APLP2 amyloid beta (A4) precursor-like protein 2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CNPY3 canopy FGF signaling regulator 3
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COL6A1 collagen, type VI, alpha 1
E2F2 E2F transcription factor 2
GPM6A glycoprotein M6A
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IFITM1 interferon induced transmembrane protein 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
MAGEA3 melanoma antigen family A3
METRN meteorin, glial cell differentiation regulator
PBLD phenazine biosynthesis-like protein domain containing
PRKACB protein kinase, cAMP-dependent, catalytic, beta
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
S100A7 S100 calcium binding protein A7
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
STC1 stanniocalcin 1
STC2 stanniocalcin 2
TOX thymocyte selection-associated high mobility group box
TPD52L1 tumor protein D52-like 1
TXNIP thioredoxin interacting protein
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
ZDHHC11 zinc finger, DHHC-type containing 11

decreased expression

Symbol Name
AIM1 absent in melanoma 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CCNA2 cyclin A2
CD36 CD36 molecule (thrombospondin receptor)
CDC25A cell division cycle 25A
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CX3CR1 chemokine (C-X3-C motif) receptor 1
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
FABP4 fatty acid binding protein 4, adipocyte
FAM208B family with sequence similarity 208, member B
FBXO11 F-box protein 11
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
GABPB1 GA binding protein transcription factor, beta subunit 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IFRD2 interferon-related developmental regulator 2
JMJD6 jumonji domain containing 6
MTF2 metal response element binding transcription factor 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
NET1 neuroepithelial cell transforming 1
NFIB nuclear factor I/B
NRIP1 nuclear receptor interacting protein 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLK1 polo-like kinase 1
PPARG peroxisome proliferator-activated receptor gamma
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
RBBP6 retinoblastoma binding protein 6
RSL1D1 ribosomal L1 domain containing 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SOX9 SRY (sex determining region Y)-box 9
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TSC22D2 TSC22 domain family, member 2
TXLNA taxilin alpha
TXNDC9 thioredoxin domain containing 9
USP22 ubiquitin specific peptidase 22
ZHX2 zinc fingers and homeoboxes 2