BRD-A11678676_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

75 genes differentially expressed following the BRD-A11678676_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AQP3 aquaporin 3 (Gill blood group)
BASP1 brain abundant, membrane attached signal protein 1
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTG1 B-cell translocation gene 1, anti-proliferative
C6ORF48 chromosome 6 open reading frame 48
CCNG2 cyclin G2
CD44 CD44 molecule (Indian blood group)
CDK19 cyclin-dependent kinase 19
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
DDIT4 DNA-damage-inducible transcript 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
ERBB3 erb-b2 receptor tyrosine kinase 3
FAM117A family with sequence similarity 117, member A
FAM63A family with sequence similarity 63, member A
FOXO4 forkhead box O4
GAA glucosidase, alpha; acid
GDF15 growth differentiation factor 15
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GRN granulin
H1FX H1 histone family, member X
HBP1 HMG-box transcription factor 1
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFITM1 interferon induced transmembrane protein 1
INSIG1 insulin induced gene 1
IRX5 iroquois homeobox 5
KLHDC2 kelch domain containing 2
MBNL2 muscleblind-like splicing regulator 2
METTL7A methyltransferase like 7A
MXI1 MAX interactor 1, dimerization protein
N4BP2L1 NEDD4 binding protein 2-like 1
NCOA2 nuclear receptor coactivator 2
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NRIP1 nuclear receptor interacting protein 1
OXR1 oxidation resistance 1
PDZK1IP1 PDZK1 interacting protein 1
RAP1GAP RAP1 GTPase activating protein
RB1CC1 RB1-inducible coiled-coil 1
RIN2 Ras and Rab interactor 2
RNF167 ring finger protein 167
SEPP1 selenoprotein P, plasma, 1
SERINC3 serine incorporator 3
TM4SF1 transmembrane 4 L six family member 1
TNNT1 troponin T type 1 (skeletal, slow)
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
WIPI1 WD repeat domain, phosphoinositide interacting 1
WLS wntless Wnt ligand secretion mediator
ZMYND8 zinc finger, MYND-type containing 8

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
ANPEP alanyl (membrane) aminopeptidase
CDC25A cell division cycle 25A
CDK2AP1 cyclin-dependent kinase 2 associated protein 1
DLK1 delta-like 1 homolog (Drosophila)
DNM1L dynamin 1-like
DPYSL3 dihydropyrimidinase-like 3
EIF5A eukaryotic translation initiation factor 5A
EMP1 epithelial membrane protein 1
GABPB1 GA binding protein transcription factor, beta subunit 1
GNAS GNAS complex locus
GRWD1 glutamate-rich WD repeat containing 1
HOMER2 homer scaffolding protein 2
KRT7 keratin 7, type II
LDHB lactate dehydrogenase B
MAGEA3 melanoma antigen family A3
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
NT5DC2 5'-nucleotidase domain containing 2
PFKP phosphofructokinase, platelet
PHLDA1 pleckstrin homology-like domain, family A, member 1
PRAME preferentially expressed antigen in melanoma
PTGDS prostaglandin D2 synthase 21kDa (brain)
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)