BRD-A11678676_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

67 genes differentially expressed following the BRD-A11678676_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ANXA4 annexin A4
AREG amphiregulin
BEX4 brain expressed, X-linked 4
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD44 CD44 molecule (Indian blood group)
CD9 CD9 molecule
CLCA4 chloride channel accessory 4
CXADR coxsackie virus and adenovirus receptor
DEPTOR DEP domain containing MTOR-interacting protein
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLK1 delta-like 1 homolog (Drosophila)
DPYSL3 dihydropyrimidinase-like 3
GSN gelsolin
GSTM3 glutathione S-transferase mu 3 (brain)
HIST2H2BE histone cluster 2, H2be
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IER5 immediate early response 5
KLF6 Kruppel-like factor 6
KRT20 keratin 20, type I
LOC100505650 uncharacterized LOC100505650
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP7 microtubule-associated protein 7
MEIS1 Meis homeobox 1
MSMO1 methylsterol monooxygenase 1
MXI1 MAX interactor 1, dimerization protein
NDRG1 N-myc downstream regulated 1
PLCB4 phospholipase C, beta 4
PRUNE2 prune homolog 2 (Drosophila)
RAB40B RAB40B, member RAS oncogene family
SEPP1 selenoprotein P, plasma, 1
SH3BGRL SH3 domain binding glutamate-rich protein like
SPRY2 sprouty homolog 2 (Drosophila)
VNN1 vanin 1
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
AURKA aurora kinase A
BIRC5 baculoviral IAP repeat containing 5
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CA12 carbonic anhydrase XII
CCNA2 cyclin A2
CD14 CD14 molecule
CDC20 cell division cycle 20
CDKN3 cyclin-dependent kinase inhibitor 3
CENPA centromere protein A
CENPF centromere protein F, 350/400kDa
COTL1 coactosin-like F-actin binding protein 1
DEPDC1 DEP domain containing 1
DLD dihydrolipoamide dehydrogenase
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
FAM129A family with sequence similarity 129, member A
IFI30 interferon, gamma-inducible protein 30
IGFBP6 insulin-like growth factor binding protein 6
KIF20A kinesin family member 20A
KIF2C kinesin family member 2C
METRN meteorin, glial cell differentiation regulator
NQO1 NAD(P)H dehydrogenase, quinone 1
ODC1 ornithine decarboxylase 1
PHGDH phosphoglycerate dehydrogenase
PLK1 polo-like kinase 1
PTGES prostaglandin E synthase
SPAG5 sperm associated antigen 5
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TPX2 TPX2, microtubule-associated
UBE2S ubiquitin-conjugating enzyme E2S