BRD-A11678676_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

67 genes differentially expressed following the BRD-A11678676_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARMCX1 armadillo repeat containing, X-linked 1
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CCNG1 cyclin G1
CCNG2 cyclin G2
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
FOXO4 forkhead box O4
GNB5 guanine nucleotide binding protein (G protein), beta 5
GPX4 glutathione peroxidase 4
GSTP1 glutathione S-transferase pi 1
HBP1 HMG-box transcription factor 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2AC histone cluster 1, H2ac
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
KLHL24 kelch-like family member 24
LXN latexin
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MDK midkine (neurite growth-promoting factor 2)
MVP major vault protein
RAP1GAP RAP1 GTPase activating protein
SKAP2 src kinase associated phosphoprotein 2
SLC44A4 solute carrier family 44, member 4
SOX4 SRY (sex determining region Y)-box 4
THBS1 thrombospondin 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNNT1 troponin T type 1 (skeletal, slow)
TST thiosulfate sulfurtransferase (rhodanese)
TUBA1A tubulin, alpha 1a
VCAN versican
WIPI1 WD repeat domain, phosphoinositide interacting 1

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
ALG8 ALG8, alpha-1,3-glucosyltransferase
BOP1 block of proliferation 1
CCND1 cyclin D1
CDC25A cell division cycle 25A
COL3A1 collagen, type III, alpha 1
COL4A6 collagen, type IV, alpha 6
CPE carboxypeptidase E
CTPS1 CTP synthase 1
EGR2 early growth response 2
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
GEM GTP binding protein overexpressed in skeletal muscle
HES1 hes family bHLH transcription factor 1
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10
IGFBP7 insulin-like growth factor binding protein 7
IGKC immunoglobulin kappa constant
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KRT15 keratin 15, type I
MXRA7 matrix-remodelling associated 7
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOP16 NOP16 nucleolar protein
ODC1 ornithine decarboxylase 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PUS7 pseudouridylate synthase 7 (putative)
RPP40 ribonuclease P/MRP 40kDa subunit
S100A8 S100 calcium binding protein A8
SCG2 secretogranin II
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
TNC tenascin C
UBE3C ubiquitin protein ligase E3C