BRD-A11678676_-666_ASC_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

110 genes differentially expressed following the BRD-A11678676_-666_ASC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ANKRD10 ankyrin repeat domain 10
C10ORF10 chromosome 10 open reading frame 10
C1ORF115 chromosome 1 open reading frame 115
C3 complement component 3
CBR3 carbonyl reductase 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CERS6 ceramide synthase 6
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLU clusterin
COL11A1 collagen, type XI, alpha 1
COMP cartilage oligomeric matrix protein
CTSF cathepsin F
ELOVL6 ELOVL fatty acid elongase 6
FADS1 fatty acid desaturase 1
FTH1 ferritin, heavy polypeptide 1
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GHR growth hormone receptor
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOXA5 homeobox A5
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IL1R1 interleukin 1 receptor, type I
INSR insulin receptor
IRS2 insulin receptor substrate 2
LCN2 lipocalin 2
MAST2 microtubule associated serine/threonine kinase 2
MCOLN1 mucolipin 1
METTL7A methyltransferase like 7A
MMD monocyte to macrophage differentiation-associated
MTUS1 microtubule associated tumor suppressor 1
MXRA5 matrix-remodelling associated 5
NAMPT nicotinamide phosphoribosyltransferase
PEG3 paternally expressed 3
PEX11A peroxisomal biogenesis factor 11 alpha
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLXNC1 plexin C1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTPRE protein tyrosine phosphatase, receptor type, E
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
SELL selectin L
SFRP4 secreted frizzled-related protein 4
SLC46A3 solute carrier family 46, member 3
SPON1 spondin 1, extracellular matrix protein
STAB1 stabilin 1
THBS4 thrombospondin 4
TM4SF4 transmembrane 4 L six family member 4
TM7SF2 transmembrane 7 superfamily member 2
TMEM97 transmembrane protein 97
TOR1A torsin family 1, member A (torsin A)
WBP1L WW domain binding protein 1-like
XIST X inactive specific transcript (non-protein coding)
ZFAND5 zinc finger, AN1-type domain 5

decreased expression

Symbol Name
AK1 adenylate kinase 1
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ASNS asparagine synthetase (glutamine-hydrolyzing)
BIRC5 baculoviral IAP repeat containing 5
CD24 CD24 molecule
CDC20 cell division cycle 20
CDK7 cyclin-dependent kinase 7
CKAP4 cytoskeleton-associated protein 4
COL3A1 collagen, type III, alpha 1
CSE1L CSE1 chromosome segregation 1-like (yeast)
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ENO1 enolase 1, (alpha)
ENO2 enolase 2 (gamma, neuronal)
EPRS glutamyl-prolyl-tRNA synthetase
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FOLR1 folate receptor 1 (adult)
HES1 hes family bHLH transcription factor 1
JCHAIN joining chain of multimeric IgA and IgM
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KDM5D lysine (K)-specific demethylase 5D
LOX lysyl oxidase
LTF lactotransferrin
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NEFL neurofilament, light polypeptide
OAT ornithine aminotransferase
ODC1 ornithine decarboxylase 1
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PFKP phosphofructokinase, platelet
PFN2 profilin 2
PGAM1 phosphoglycerate mutase 1 (brain)
PGK1 phosphoglycerate kinase 1
PHGDH phosphoglycerate dehydrogenase
PHLDA1 pleckstrin homology-like domain, family A, member 1
PKM pyruvate kinase, muscle
PSAT1 phosphoserine aminotransferase 1
PSPH phosphoserine phosphatase
PYCR1 pyrroline-5-carboxylate reductase 1
RFC2 replication factor C (activator 1) 2, 40kDa
RPS4Y1 ribosomal protein S4, Y-linked 1
SCGB2A1 secretoglobin, family 2A, member 1
SEPT9 septin 9
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SMS spermine synthase
STC2 stanniocalcin 2
TGFBI transforming growth factor, beta-induced, 68kDa
TM4SF1 transmembrane 4 L six family member 1
TMEM243 transmembrane protein 243, mitochondrial
TOP2A topoisomerase (DNA) II alpha 170kDa
UBE2C ubiquitin-conjugating enzyme E2C