BRD-A11678676_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

109 genes differentially expressed following the BRD-A11678676_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG1 adhesion G protein-coupled receptor G1
ADGRG6 adhesion G protein-coupled receptor G6
ANXA5 annexin A5
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
BCL3 B-cell CLL/lymphoma 3
BHLHE41 basic helix-loop-helix family, member e41
BTG1 B-cell translocation gene 1, anti-proliferative
C3ORF14 chromosome 3 open reading frame 14
CCL20 chemokine (C-C motif) ligand 20
CCNG2 cyclin G2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN2A cyclin-dependent kinase inhibitor 2A
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CTSL cathepsin L
CXCL8 chemokine (C-X-C motif) ligand 8
F11R F11 receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FHL2 four and a half LIM domains 2
FRY furry homolog (Drosophila)
GEM GTP binding protein overexpressed in skeletal muscle
GPR137B G protein-coupled receptor 137B
GREM1 gremlin 1, DAN family BMP antagonist
HBB hemoglobin, beta
HBP1 HMG-box transcription factor 1
HMGA1 high mobility group AT-hook 1
HMOX1 heme oxygenase 1
IL11 interleukin 11
IL1R1 interleukin 1 receptor, type I
IL6 interleukin 6
KCNK1 potassium channel, two pore domain subfamily K, member 1
KIAA0226L KIAA0226-like
KLF5 Kruppel-like factor 5 (intestinal)
LIF leukemia inhibitory factor
LTBP1 latent transforming growth factor beta binding protein 1
LTBP2 latent transforming growth factor beta binding protein 2
MGLL monoglyceride lipase
MMP1 matrix metallopeptidase 1
MMP3 matrix metallopeptidase 3
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MTMR11 myotubularin related protein 11
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NRIP1 nuclear receptor interacting protein 1
PDGFA platelet-derived growth factor alpha polypeptide
PDLIM4 PDZ and LIM domain 4
PSEN1 presenilin 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SQSTM1 sequestosome 1
STX1A syntaxin 1A (brain)
TBX3 T-box 3
TGIF1 TGFB-induced factor homeobox 1
TMEM176B transmembrane protein 176B
TMEM2 transmembrane protein 2
TRIM36 tripartite motif containing 36
TSC22D1 TSC22 domain family, member 1
TXNRD1 thioredoxin reductase 1
ZC2HC1A zinc finger, C2HC-type containing 1A

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
AGTR1 angiotensin II receptor, type 1
BCHE butyrylcholinesterase
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C3 complement component 3
CALU calumenin
CCND1 cyclin D1
CCND2 cyclin D2
CDC25A cell division cycle 25A
CORO1A coronin, actin binding protein, 1A
CSRP2 cysteine and glycine-rich protein 2
CST7 cystatin F (leukocystatin)
CTSH cathepsin H
DHCR24 24-dehydrocholesterol reductase
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FABP6 fatty acid binding protein 6, ileal
GBP1 guanylate binding protein 1, interferon-inducible
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPA1A heat shock 70kDa protein 1A
HSPB1 heat shock 27kDa protein 1
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
JMJD6 jumonji domain containing 6
JUN jun proto-oncogene
KCTD12 potassium channel tetramerization domain containing 12
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MCAM melanoma cell adhesion molecule
MXRA7 matrix-remodelling associated 7
PGAM1 phosphoglycerate mutase 1 (brain)
PODXL podocalyxin-like
PRDX4 peroxiredoxin 4
PRPS1 phosphoribosyl pyrophosphate synthetase 1
PRSS23 protease, serine, 23
PTGDS prostaglandin D2 synthase 21kDa (brain)
RBPMS RNA binding protein with multiple splicing
RGS1 regulator of G-protein signaling 1
RGS5 regulator of G-protein signaling 5
RHOBTB3 Rho-related BTB domain containing 3
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SUB1 SUB1 homolog (S. cerevisiae)
TBC1D16 TBC1 domain family, member 16
TRAC T cell receptor alpha constant
ZIC1 Zic family member 1