BRD-A11095214_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

89 genes differentially expressed following the BRD-A11095214_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMIGO2 adhesion molecule with Ig-like domain 2
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BID BH3 interacting domain death agonist
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CEMIP cell migration inducing protein, hyaluronan binding
CFB complement factor B
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL10A1 collagen, type X, alpha 1
CPA3 carboxypeptidase A3 (mast cell)
CRISP3 cysteine-rich secretory protein 3
DKK3 dickkopf WNT signaling pathway inhibitor 3
ELANE elastase, neutrophil expressed
FHOD3 formin homology 2 domain containing 3
H1F0 H1 histone family, member 0
KRT18 keratin 18, type I
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
MSLN mesothelin
MSMB microseminoprotein, beta-
MYB v-myb avian myeloblastosis viral oncogene homolog
P3H2 prolyl 3-hydroxylase 2
PLCB4 phospholipase C, beta 4
PTPRE protein tyrosine phosphatase, receptor type, E
S100A8 S100 calcium binding protein A8
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SDC1 syndecan 1
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFRP4 secreted frizzled-related protein 4
SGK1 serum/glucocorticoid regulated kinase 1
SIRPA signal-regulatory protein alpha
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SORBS2 sorbin and SH3 domain containing 2
SRGN serglycin
TRIB3 tribbles pseudokinase 3
VTCN1 V-set domain containing T cell activation inhibitor 1
WT1 Wilms tumor 1

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
ANXA3 annexin A3
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
BAG2 BCL2-associated athanogene 2
BCLAF1 BCL2-associated transcription factor 1
C1QB complement component 1, q subcomponent, B chain
C8ORF4 chromosome 8 open reading frame 4
CD163 CD163 molecule
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRYAB crystallin, alpha B
CXCL8 chemokine (C-X-C motif) ligand 8
DHRS7 dehydrogenase/reductase (SDR family) member 7
ERAP2 endoplasmic reticulum aminopeptidase 2
F2R coagulation factor II (thrombin) receptor
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM46A family with sequence similarity 46, member A
FERMT2 fermitin family member 2
FKBP5 FK506 binding protein 5
GPX3 glutathione peroxidase 3
GSTA4 glutathione S-transferase alpha 4
HLTF helicase-like transcription factor
IFI44L interferon-induced protein 44-like
IL13RA2 interleukin 13 receptor, alpha 2
IL1RL1 interleukin 1 receptor-like 1
IQGAP1 IQ motif containing GTPase activating protein 1
ISG15 ISG15 ubiquitin-like modifier
KRT10 keratin 10, type I
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MARCKS myristoylated alanine-rich protein kinase C substrate
MGP matrix Gla protein
MSRB2 methionine sulfoxide reductase B2
NFIB nuclear factor I/B
PALLD palladin, cytoskeletal associated protein
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PEBP1 phosphatidylethanolamine binding protein 1
PLTP phospholipid transfer protein
PNMA1 paraneoplastic Ma antigen 1
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
PSIP1 PC4 and SFRS1 interacting protein 1
RDX radixin
SEPP1 selenoprotein P, plasma, 1
SPARCL1 SPARC-like 1 (hevin)
SPATS2L spermatogenesis associated, serine-rich 2-like
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TJP2 tight junction protein 2
TMEM47 transmembrane protein 47