BRD-A11087911_-666_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-A11087911_-666_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGR2 anterior gradient 2
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ASRGL1 asparaginase like 1
CCDC92 coiled-coil domain containing 92
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CLCA1 chloride channel accessory 1
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
DCXR dicarbonyl/L-xylulose reductase
DUSP6 dual specificity phosphatase 6
G6PD glucose-6-phosphate dehydrogenase
GPX2 glutathione peroxidase 2
GSTM3 glutathione S-transferase mu 3 (brain)
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
MIR22HG MIR22 host gene
MMP1 matrix metallopeptidase 1
NELL2 NEL-like 2 (chicken)
ODC1 ornithine decarboxylase 1
PEG10 paternally expressed 10
PNKP polynucleotide kinase 3'-phosphatase
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC26A3 solute carrier family 26 (anion exchanger), member 3
TMSB15A thymosin beta 15a
TSPAN3 tetraspanin 3
TUBB2A tubulin, beta 2A class IIa
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
C1R complement component 1, r subcomponent
C1S complement component 1, s subcomponent
C3 complement component 3
CALD1 caldesmon 1
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
CRABP2 cellular retinoic acid binding protein 2
CSTA cystatin A (stefin A)
FABP7 fatty acid binding protein 7, brain
HACD3 3-hydroxyacyl-CoA dehydratase 3
HBB hemoglobin, beta
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
IFI44 interferon-induced protein 44
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP3 insulin-like growth factor binding protein 3
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
KANK1 KN motif and ankyrin repeat domains 1
KLK10 kallikrein-related peptidase 10
KRT14 keratin 14, type I
KRT6B keratin 6B, type II
LIPA lipase A, lysosomal acid, cholesterol esterase
LOX lysyl oxidase
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MYC v-myc avian myelocytomatosis viral oncogene homolog
NDRG2 NDRG family member 2
PERP PERP, TP53 apoptosis effector
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
RAB25 RAB25, member RAS oncogene family
RBPMS RNA binding protein with multiple splicing
S100A2 S100 calcium binding protein A2
S100A4 S100 calcium binding protein A4
SCEL sciellin
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC43A3 solute carrier family 43, member 3
SLPI secretory leukocyte peptidase inhibitor
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
TACSTD2 tumor-associated calcium signal transducer 2
TGFBI transforming growth factor, beta-induced, 68kDa
TM4SF1 transmembrane 4 L six family member 1
VGLL1 vestigial-like family member 1