BRD-A11087911_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

122 genes differentially expressed following the BRD-A11087911_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACVR1 activin A receptor, type I
ASPN asporin
BEX4 brain expressed, X-linked 4
CADM1 cell adhesion molecule 1
CCNE2 cyclin E2
CD52 CD52 molecule
CFB complement factor B
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIC2 cysteine-rich hydrophobic domain 2
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
COL11A1 collagen, type XI, alpha 1
COMP cartilage oligomeric matrix protein
CXADR coxsackie virus and adenovirus receptor
DCN decorin
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP6 dual specificity phosphatase 6
EDNRA endothelin receptor type A
EGR1 early growth response 1
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FABP4 fatty acid binding protein 4, adipocyte
FAM134B family with sequence similarity 134, member B
GADD45B growth arrest and DNA-damage-inducible, beta
GEM GTP binding protein overexpressed in skeletal muscle
GREM1 gremlin 1, DAN family BMP antagonist
GSTM3 glutathione S-transferase mu 3 (brain)
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BC histone cluster 1, H2bc
HIST1H2BD histone cluster 1, H2bd
HIST1H2BE histone cluster 1, H2be
HIST1H2BF histone cluster 1, H2bf
HIST1H2BK histone cluster 1, H2bk
HIST1H4H histone cluster 1, H4h
HIST2H2BE histone cluster 2, H2be
HIST3H2A histone cluster 3, H2a
IFI6 interferon, alpha-inducible protein 6
IL1RAP interleukin 1 receptor accessory protein
KRT23 keratin 23, type I
MYO1B myosin IB
NR4A2 nuclear receptor subfamily 4, group A, member 2
ORM1 orosomucoid 1
PDLIM3 PDZ and LIM domain 3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RGS2 regulator of G-protein signaling 2
RHOB ras homolog family member B
RNASE6 ribonuclease, RNase A family, k6
S100A6 S100 calcium binding protein A6
SDC2 syndecan 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SORBS1 sorbin and SH3 domain containing 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SSPN sarcospan
STC1 stanniocalcin 1
SULF1 sulfatase 1
TDO2 tryptophan 2,3-dioxygenase
TFRC transferrin receptor
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TOB1 transducer of ERBB2, 1
TPD52L1 tumor protein D52-like 1
TSPAN13 tetraspanin 13
TUBB2B tubulin, beta 2B class IIb
TUSC3 tumor suppressor candidate 3
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
ADA adenosine deaminase
ADAM10 ADAM metallopeptidase domain 10
ADGRE5 adhesion G protein-coupled receptor E5
AHNAK AHNAK nucleoprotein
ALCAM activated leukocyte cell adhesion molecule
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANXA1 annexin A1
B3GNT1
BASP1 brain abundant, membrane attached signal protein 1
CAPG capping protein (actin filament), gelsolin-like
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CFLAR CASP8 and FADD-like apoptosis regulator
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CTSH cathepsin H
CYTH1 cytohesin 1
ERBB2 erb-b2 receptor tyrosine kinase 2
FOLR1 folate receptor 1 (adult)
GNAS GNAS complex locus
GTF2I general transcription factor IIi
HMGA2 high mobility group AT-hook 2
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
JADE2 jade family PHD finger 2
KIF14 kinesin family member 14
MARCKS myristoylated alanine-rich protein kinase C substrate
MICALL1 MICAL-like 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
PDLIM2 PDZ and LIM domain 2 (mystique)
PFKP phosphofructokinase, platelet
PFN2 profilin 2
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PLAC8 placenta-specific 8
PLK1 polo-like kinase 1
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RFC2 replication factor C (activator 1) 2, 40kDa
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLIT2 slit homolog 2 (Drosophila)
SORBS3 sorbin and SH3 domain containing 3
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TMPO thymopoietin
TNIP1 TNFAIP3 interacting protein 1
TRIM16 tripartite motif containing 16
TSPAN8 tetraspanin 8
TUBB tubulin, beta class I
VCAN versican
XPO7 exportin 7