BRD-A11087911_-666_A549_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

116 genes differentially expressed following the BRD-A11087911_-666_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ANKRD10 ankyrin repeat domain 10
C10ORF10 chromosome 10 open reading frame 10
CA2 carbonic anhydrase II
CAAP1 caspase activity and apoptosis inhibitor 1
CCP110 centriolar coiled coil protein 110kDa
CD9 CD9 molecule
CKB creatine kinase, brain
CPB1 carboxypeptidase B1 (tissue)
CYB5R1 cytochrome b5 reductase 1
DCN decorin
DMD dystrophin
DSP desmoplakin
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
FBP1 fructose-1,6-bisphosphatase 1
GSTZ1 glutathione S-transferase zeta 1
H2BFS H2B histone family, member S (pseudogene)
HEPH hephaestin
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
IDO1 indoleamine 2,3-dioxygenase 1
IER5 immediate early response 5
IFITM1 interferon induced transmembrane protein 1
LGALS1 lectin, galactoside-binding, soluble, 1
LRPPRC leucine-rich pentatricopeptide repeat containing
MFAP5 microfibrillar associated protein 5
MMP12 matrix metallopeptidase 12
MYB v-myb avian myeloblastosis viral oncogene homolog
NID2 nidogen 2 (osteonidogen)
NXN nucleoredoxin
OAT ornithine aminotransferase
OLFM4 olfactomedin 4
PDLIM3 PDZ and LIM domain 3
PLAT plasminogen activator, tissue
PLIN2 perilipin 2
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RCAN2 regulator of calcineurin 2
REG1A regenerating islet-derived 1 alpha
REG1B regenerating islet-derived 1 beta
RGS4 regulator of G-protein signaling 4
SAT1 spermidine/spermine N1-acetyltransferase 1
SH3YL1 SH3 and SYLF domain containing 1
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SOX9 SRY (sex determining region Y)-box 9
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SULF1 sulfatase 1
THBS2 thrombospondin 2
TMEM30B transmembrane protein 30B
TMOD1 tropomodulin 1
TPD52L1 tumor protein D52-like 1
TST thiosulfate sulfurtransferase (rhodanese)
XIST X inactive specific transcript (non-protein coding)
XK X-linked Kx blood group
ZNF423 zinc finger protein 423

decreased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
CADM1 cell adhesion molecule 1
CALR calreticulin
CD24 CD24 molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK14 cyclin-dependent kinase 14
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CXCL12 chemokine (C-X-C motif) ligand 12
DEFB1 defensin, beta 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EMP1 epithelial membrane protein 1
FBN2 fibrillin 2
FOLR1 folate receptor 1 (adult)
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGLJ3 immunoglobulin lambda joining 3
KDM5D lysine (K)-specific demethylase 5D
LMO4 LIM domain only 4
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP9 matrix metallopeptidase 9
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
PDLIM2 PDZ and LIM domain 2 (mystique)
PLK1 polo-like kinase 1
PTN pleiotrophin
RAB2A RAB2A, member RAS oncogene family
RAD23B RAD23 homolog B (S. cerevisiae)
RAP1GAP RAP1 GTPase activating protein
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RPL38 ribosomal protein L38
S100A11 S100 calcium binding protein A11
SRSF1 serine/arginine-rich splicing factor 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TRAC T cell receptor alpha constant
TRBC1 T cell receptor beta constant 1
TXN thioredoxin
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon