BRD-A11007541_B4313_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-A11007541_B4313_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATF3 activating transcription factor 3
BLNK B-cell linker
CACYBP calcyclin binding protein
CD52 CD52 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEP57 centrosomal protein 57kDa
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CYBB cytochrome b-245, beta polypeptide
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DUSP2 dual specificity phosphatase 2
EZR ezrin
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GADD45A growth arrest and DNA-damage-inducible, alpha
GPNMB glycoprotein (transmembrane) nmb
HECA headcase homolog (Drosophila)
HIST1H1C histone cluster 1, H1c
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPB8 heat shock 22kDa protein 8
IFI6 interferon, alpha-inducible protein 6
IGHD immunoglobulin heavy constant delta
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
INSIG1 insulin induced gene 1
JUN jun proto-oncogene
KIF5C kinesin family member 5C
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP7 microtubule-associated protein 7
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MFSD10 major facilitator superfamily domain containing 10
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SST somatostatin
TIMP3 TIMP metallopeptidase inhibitor 3
TMSB15A thymosin beta 15a
TPD52L1 tumor protein D52-like 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
WIF1 WNT inhibitory factor 1
XBP1 X-box binding protein 1
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
C3 complement component 3
CA12 carbonic anhydrase XII
CCND1 cyclin D1
CDCA4 cell division cycle associated 4
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
HOXA10 homeobox A10
IER3 immediate early response 3
NFIB nuclear factor I/B
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NRN1 neuritin 1
NUP85 nucleoporin 85kDa
PI3 peptidase inhibitor 3, skin-derived
PLK1 polo-like kinase 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
S100A7 S100 calcium binding protein A7
SRPX sushi-repeat containing protein, X-linked
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TOP2A topoisomerase (DNA) II alpha 170kDa
TRIM29 tripartite motif containing 29