BRD-A11007541_B4313_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

125 genes differentially expressed following the BRD-A11007541_B4313_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ADM adrenomedullin
AKAP13 A kinase (PRKA) anchor protein 13
ATF3 activating transcription factor 3
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
AVPI1 arginine vasopressin-induced 1
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRP2 cysteine and glycine-rich protein 2
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP1 dual specificity phosphatase 1
DUSP5 dual specificity phosphatase 5
FCMR Fc fragment of IgM receptor
FOSL2 FOS-like antigen 2
GABARAPL1 GABA(A) receptor-associated protein like 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GLA galactosidase, alpha
GNAS GNAS complex locus
GPATCH8 G patch domain containing 8
GPRC5A G protein-coupled receptor, class C, group 5, member A
HECA headcase homolog (Drosophila)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IFRD1 interferon-related developmental regulator 1
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IL11 interleukin 11
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KIAA0907 KIAA0907
LBH limb bud and heart development
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGEA1 melanoma antigen family A1
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA5 melanoma antigen family A5
MAGEA6 melanoma antigen family A6
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MCOLN1 mucolipin 1
MIR22HG MIR22 host gene
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP1 matrix metallopeptidase 1
MMP19 matrix metallopeptidase 19
NAMPT nicotinamide phosphoribosyltransferase
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFIL3 nuclear factor, interleukin 3 regulated
NR4A3 nuclear receptor subfamily 4, group A, member 3
NUP98 nucleoporin 98kDa
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RGCC regulator of cell cycle
RHOB ras homolog family member B
RIOK3 RIO kinase 3
RNMT RNA (guanine-7-) methyltransferase
SERINC5 serine incorporator 5
SFN stratifin
SIK1 salt-inducible kinase 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SQSTM1 sequestosome 1
SSX1 synovial sarcoma, X breakpoint 1
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
ZFP36 ZFP36 ring finger protein
ZNF274 zinc finger protein 274

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
AIM1 absent in melanoma 1
ALCAM activated leukocyte cell adhesion molecule
AURKA aurora kinase A
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BIRC5 baculoviral IAP repeat containing 5
C2CD5 C2 calcium-dependent domain containing 5
CA12 carbonic anhydrase XII
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCNA2 cyclin A2
CCND1 cyclin D1
CDK1 cyclin-dependent kinase 1
CENPA centromere protein A
CEP55 centrosomal protein 55kDa
CPA3 carboxypeptidase A3 (mast cell)
CYBA cytochrome b-245, alpha polypeptide
DAPK1 death-associated protein kinase 1
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GTF3A general transcription factor IIIA
HMGA2 high mobility group AT-hook 2
ICAM2 intercellular adhesion molecule 2
ICMT isoprenylcysteine carboxyl methyltransferase
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIAA0101 KIAA0101
KIF20A kinesin family member 20A
KIF2C kinesin family member 2C
LAMC1 laminin, gamma 1 (formerly LAMB2)
LIPA lipase A, lysosomal acid, cholesterol esterase
LOXL1 lysyl oxidase-like 1
LY96 lymphocyte antigen 96
NFIB nuclear factor I/B
NR2F2 nuclear receptor subfamily 2, group F, member 2
NREP neuronal regeneration related protein
PCYOX1L prenylcysteine oxidase 1 like
PON2 paraoxonase 2
PTGIS prostaglandin I2 (prostacyclin) synthase
PYCARD PYD and CARD domain containing
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RFC2 replication factor C (activator 1) 2, 40kDa
RPS4Y1 ribosomal protein S4, Y-linked 1
SMAD1 SMAD family member 1
SPDEF SAM pointed domain containing ETS transcription factor
STEAP1 six transmembrane epithelial antigen of the prostate 1
SULF1 sulfatase 1
TOP2A topoisomerase (DNA) II alpha 170kDa
TYMS thymidylate synthetase