BRD-A11007541_B4313_NEU_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

159 genes differentially expressed following the BRD-A11007541_B4313_NEU_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAA2 acetyl-CoA acyltransferase 2
ADAMDEC1 ADAM-like, decysin 1
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIRF adipogenesis regulatory factor
AK4 adenylate kinase 4
AMIGO2 adhesion molecule with Ig-like domain 2
AQP9 aquaporin 9
C1QA complement component 1, q subcomponent, A chain
CALB1 calbindin 1, 28kDa
CALB2 calbindin 2
CFD complement factor D (adipsin)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
COL3A1 collagen, type III, alpha 1
CTSD cathepsin D
CTSZ cathepsin Z
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL9 chemokine (C-X-C motif) ligand 9
CYBA cytochrome b-245, alpha polypeptide
DLK1 delta-like 1 homolog (Drosophila)
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGFL6 EGF-like-domain, multiple 6
EPAS1 endothelial PAS domain protein 1
EREG epiregulin
G0S2 G0/G1 switch 2
GBP1 guanylate binding protein 1, interferon-inducible
GBP2 guanylate binding protein 2, interferon-inducible
GCH1 GTP cyclohydrolase 1
GSTM3 glutathione S-transferase mu 3 (brain)
H2BFS H2B histone family, member S (pseudogene)
HADH hydroxyacyl-CoA dehydrogenase
HIST1H1C histone cluster 1, H1c
HK2 hexokinase 2
HTRA1 HtrA serine peptidase 1
IFI30 interferon, gamma-inducible protein 30
ISG15 ISG15 ubiquitin-like modifier
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MIR22HG MIR22 host gene
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MYL2 myosin, light chain 2, regulatory, cardiac, slow
NNMT nicotinamide N-methyltransferase
PDE10A phosphodiesterase 10A
PDLIM1 PDZ and LIM domain 1
PENK proenkephalin
PLEK pleckstrin
PLIN1 perilipin 1
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PSENEN presenilin enhancer gamma secretase subunit
PTGDS prostaglandin D2 synthase 21kDa (brain)
RGS5 regulator of G-protein signaling 5
S100A12 S100 calcium binding protein A12
S100A6 S100 calcium binding protein A6
S100A9 S100 calcium binding protein A9
SAT1 spermidine/spermine N1-acetyltransferase 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SOCS2 suppressor of cytokine signaling 2
STAT1 signal transducer and activator of transcription 1, 91kDa
TDO2 tryptophan 2,3-dioxygenase
TFF3 trefoil factor 3 (intestinal)
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TLR4 toll-like receptor 4
TPBG trophoblast glycoprotein
TPD52L1 tumor protein D52-like 1
VCAM1 vascular cell adhesion molecule 1
ZNF165 zinc finger protein 165

decreased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALCAM activated leukocyte cell adhesion molecule
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
BAZ2B bromodomain adjacent to zinc finger domain, 2B
BCL2 B-cell CLL/lymphoma 2
CAPRIN1 cell cycle associated protein 1
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CASP10 caspase 10, apoptosis-related cysteine peptidase
CELF2 CUGBP, Elav-like family member 2
CERS6 ceramide synthase 6
CHD9 chromodomain helicase DNA binding protein 9
CYFIP2 cytoplasmic FMR1 interacting protein 2
DLG5 discs, large homolog 5 (Drosophila)
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EDNRA endothelin receptor type A
EMX2 empty spiracles homeobox 2
EPHA3 EPH receptor A3
ETV5 ets variant 5
FABP7 fatty acid binding protein 7, brain
FAM134B family with sequence similarity 134, member B
FZD7 frizzled class receptor 7
GAS1 growth arrest-specific 1
GDF15 growth differentiation factor 15
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ITM2A integral membrane protein 2A
JAK1 Janus kinase 1
KIF2C kinesin family member 2C
KLHDC10 kelch domain containing 10
KLHL9 kelch-like family member 9
LPP LIM domain containing preferred translocation partner in lipoma
MACF1 microtubule-actin crosslinking factor 1
MAGED1 melanoma antigen family D1
MED1 mediator complex subunit 1
MLEC malectin
MYB v-myb avian myeloblastosis viral oncogene homolog
N4BP2L2 NEDD4 binding protein 2-like 2
NCALD neurocalcin delta
NEBL nebulette
NISCH nischarin
NR2F2 nuclear receptor subfamily 2, group F, member 2
NREP neuronal regeneration related protein
NRIP1 nuclear receptor interacting protein 1
PDLIM5 PDZ and LIM domain 5
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PRSS23 protease, serine, 23
PSD3 pleckstrin and Sec7 domain containing 3
RBM5 RNA binding motif protein 5
RNH1 ribonuclease/angiogenin inhibitor 1
RNMT RNA (guanine-7-) methyltransferase
RUFY3 RUN and FYVE domain containing 3
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SON SON DNA binding protein
SOX2 SRY (sex determining region Y)-box 2
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPTBN1 spectrin, beta, non-erythrocytic 1
SRSF1 serine/arginine-rich splicing factor 1
SS18 synovial sarcoma translocation, chromosome 18
SUCO SUN domain containing ossification factor
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TCF12 transcription factor 12
TCF4 transcription factor 4
TGFBI transforming growth factor, beta-induced, 68kDa
TGM2 transglutaminase 2
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM255A transmembrane protein 255A
TNC tenascin C
TOP2B topoisomerase (DNA) II beta 180kDa
TOX3 TOX high mobility group box family member 3
TRIM22 tripartite motif containing 22
TTC3 tetratricopeptide repeat domain 3
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
URI1 URI1, prefoldin-like chaperone
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VEZF1 vascular endothelial zinc finger 1
VGLL4 vestigial-like family member 4
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae)
WNT5A wingless-type MMTV integration site family, member 5A
YLPM1 YLP motif containing 1
ZBTB20 zinc finger and BTB domain containing 20
ZC3H13 zinc finger CCCH-type containing 13
ZEB1 zinc finger E-box binding homeobox 1
ZKSCAN1 zinc finger with KRAB and SCAN domains 1
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF217 zinc finger protein 217