BRD-A11007541_B4313_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

67 genes differentially expressed following the BRD-A11007541_B4313_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BGN biglycan
BHLHE41 basic helix-loop-helix family, member e41
BLNK B-cell linker
CA2 carbonic anhydrase II
CD36 CD36 molecule (thrombospondin receptor)
COL1A1 collagen, type I, alpha 1
CPE carboxypeptidase E
CTSZ cathepsin Z
CXCL8 chemokine (C-X-C motif) ligand 8
DEPTOR DEP domain containing MTOR-interacting protein
ENDOD1 endonuclease domain containing 1
ENOPH1 enolase-phosphatase 1
FOLR1 folate receptor 1 (adult)
GRWD1 glutamate-rich WD repeat containing 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MPPED2 metallophosphoesterase domain containing 2
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
PLK2 polo-like kinase 2
RGS2 regulator of G-protein signaling 2
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
S100A10 S100 calcium binding protein A10
SCD5 stearoyl-CoA desaturase 5
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SNAI2 snail family zinc finger 2
SOX9 SRY (sex determining region Y)-box 9
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)

decreased expression

Symbol Name
ANG angiogenin, ribonuclease, RNase A family, 5
APMAP adipocyte plasma membrane associated protein
ARPP19 cAMP-regulated phosphoprotein, 19kDa
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CERS6 ceramide synthase 6
CFI complement factor I
CLU clusterin
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
FADS1 fatty acid desaturase 1
FAM129A family with sequence similarity 129, member A
FPGS folylpolyglutamate synthase
GLS glutaminase
HOXC6 homeobox C6
IL6ST interleukin 6 signal transducer
INSIG1 insulin induced gene 1
ITFG1 integrin alpha FG-GAP repeat containing 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MAOA monoamine oxidase A
MATN2 matrilin 2
NEBL nebulette
NUP85 nucleoporin 85kDa
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PRUNE2 prune homolog 2 (Drosophila)
PSD3 pleckstrin and Sec7 domain containing 3
PTPRC protein tyrosine phosphatase, receptor type, C
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RNASE4 ribonuclease, RNase A family, 4
RNF167 ring finger protein 167
RPIA ribose 5-phosphate isomerase A
SIAH2 siah E3 ubiquitin protein ligase 2
STX1A syntaxin 1A (brain)
TGFBR3 transforming growth factor, beta receptor III
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
UGDH UDP-glucose 6-dehydrogenase
ZBTB16 zinc finger and BTB domain containing 16
ZBTB18 zinc finger and BTB domain containing 18