BRD-A10715913_SULPIRIDE_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

184 genes differentially expressed following the BRD-A10715913_SULPIRIDE_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTG2 actin, gamma 2, smooth muscle, enteric
ADM adrenomedullin
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA1 annexin A1
ANXA2 annexin A2
AQP3 aquaporin 3 (Gill blood group)
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARMCX1 armadillo repeat containing, X-linked 1
BHLHE41 basic helix-loop-helix family, member e41
BLNK B-cell linker
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C1ORF106 chromosome 1 open reading frame 106
CAPN2 calpain 2, (m/II) large subunit
CASP10 caspase 10, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCND2 cyclin D2
CCR2 chemokine (C-C motif) receptor 2
CD44 CD44 molecule (Indian blood group)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH3 cadherin 3, type 1, P-cadherin (placental)
CECR1 cat eye syndrome chromosome region, candidate 1
COL4A5 collagen, type IV, alpha 5
COL4A6 collagen, type IV, alpha 6
CRABP2 cellular retinoic acid binding protein 2
CSTA cystatin A (stefin A)
CXCR4 chemokine (C-X-C motif) receptor 4
CYBB cytochrome b-245, beta polypeptide
CYTIP cytohesin 1 interacting protein
DDR1 discoidin domain receptor tyrosine kinase 1
DEGS1 delta(4)-desaturase, sphingolipid 1
DPYD dihydropyrimidine dehydrogenase
ELANE elastase, neutrophil expressed
FAM129A family with sequence similarity 129, member A
FAM13A family with sequence similarity 13, member A
FAM69A family with sequence similarity 69, member A
FGL2 fibrinogen-like 2
FHL1 four and a half LIM domains 1
FHOD3 formin homology 2 domain containing 3
FILIP1L filamin A interacting protein 1-like
FZD1 frizzled class receptor 1
GALC galactosylceramidase
GPRASP1 G protein-coupled receptor associated sorting protein 1
GUSBP11 glucuronidase, beta pseudogene 11
H2AFV H2A histone family, member V
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HOMER3 homer scaffolding protein 3
HOXB2 homeobox B2
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IFI16 interferon, gamma-inducible protein 16
IFT57 intraflagellar transport 57
IGFBP5 insulin-like growth factor binding protein 5
IGL immunoglobulin lambda locus
IGLV2-23 immunoglobulin lambda variable 2-23
IL27RA interleukin 27 receptor, alpha
IL2RG interleukin 2 receptor, gamma
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
JUN jun proto-oncogene
KIAA1033 KIAA1033
KRT13 keratin 13, type I
LCN2 lipocalin 2
LPAR6 lysophosphatidic acid receptor 6
LYZ lysozyme
MAGEB2 melanoma antigen family B2
MDFIC MyoD family inhibitor domain containing
MEF2C myocyte enhancer factor 2C
MEIS2 Meis homeobox 2
MNDA myeloid cell nuclear differentiation antigen
MPO myeloperoxidase
MSMB microseminoprotein, beta-
MZB1 marginal zone B and B1 cell-specific protein
NELL2 NEL-like 2 (chicken)
NOX4 NADPH oxidase 4
NR1H2 nuclear receptor subfamily 1, group H, member 2
OLFM4 olfactomedin 4
P3H2 prolyl 3-hydroxylase 2
PALLD palladin, cytoskeletal associated protein
PDLIM3 PDZ and LIM domain 3
PECAM1 platelet/endothelial cell adhesion molecule 1
PERP PERP, TP53 apoptosis effector
PLBD1 phospholipase B domain containing 1
PLN phospholamban
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
PNMAL1 paraneoplastic Ma antigen family-like 1
PRTN3 proteinase 3
PXN paxillin
QPCT glutaminyl-peptide cyclotransferase
RAB27A RAB27A, member RAS oncogene family
RAB31 RAB31, member RAS oncogene family
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGCC regulator of cell cycle
RGS5 regulator of G-protein signaling 5
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNASE4 ribonuclease, RNase A family, 4
RNASE6 ribonuclease, RNase A family, k6
RNH1 ribonuclease/angiogenin inhibitor 1
RTN1 reticulon 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SPAG4 sperm associated antigen 4
STC1 stanniocalcin 1
STX1A syntaxin 1A (brain)
SULF1 sulfatase 1
SUN1 Sad1 and UNC84 domain containing 1
TGFA transforming growth factor, alpha
TLN1 talin 1
TLR4 toll-like receptor 4
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM255A transmembrane protein 255A
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPM2 tropomyosin 2 (beta)
TRIM2 tripartite motif containing 2
UBE2L6 ubiquitin-conjugating enzyme E2L 6
VEGFA vascular endothelial growth factor A
WDR7 WD repeat domain 7
ZFP36 ZFP36 ring finger protein
ZFPM2 zinc finger protein, FOG family member 2
ZNF274 zinc finger protein 274
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACLY ATP citrate lyase
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADIRF adipogenesis regulatory factor
AK4 adenylate kinase 4
ALCAM activated leukocyte cell adhesion molecule
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
CCND1 cyclin D1
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN3 cyclin-dependent kinase inhibitor 3
CGA glycoprotein hormones, alpha polypeptide
CKS2 CDC28 protein kinase regulatory subunit 2
CLTC clathrin, heavy chain (Hc)
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EIF5A eukaryotic translation initiation factor 5A
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GSTM3 glutathione S-transferase mu 3 (brain)
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
IGFBP4 insulin-like growth factor binding protein 4
KIF1BP KIF1 binding protein
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MARCKSL1 MARCKS-like 1
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1M metallothionein 1M
MT1X metallothionein 1X
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa
NGRN neugrin, neurite outgrowth associated
PCSK6 proprotein convertase subtilisin/kexin type 6
PEBP1 phosphatidylethanolamine binding protein 1
PHF20 PHD finger protein 20
PON2 paraoxonase 2
PPA1 pyrophosphatase (inorganic) 1
PRDX6 peroxiredoxin 6
PRKCZ protein kinase C, zeta
PTP4A1 protein tyrosine phosphatase type IVA, member 1
QDPR quinoid dihydropteridine reductase
RCN2 reticulocalbin 2, EF-hand calcium binding domain
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RPL37A ribosomal protein L37a
RPS11 ribosomal protein S11
RPS21 ribosomal protein S21
RPS27L ribosomal protein S27-like
SCAND1 SCAN domain containing 1
SCYL3 SCY1-like 3 (S. cerevisiae)
SFTPA2 surfactant protein A2
SKP1 S-phase kinase-associated protein 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TM4SF1 transmembrane 4 L six family member 1
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TSPAN13 tetraspanin 13
TSPAN3 tetraspanin 3
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
WSB2 WD repeat and SOCS box containing 2