BRD-A10662413_Prenylamine lactate_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

90 genes differentially expressed following the BRD-A10662413_Prenylamine lactate_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOA1 apolipoprotein A-I
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BLNK B-cell linker
C10ORF10 chromosome 10 open reading frame 10
CA2 carbonic anhydrase II
CASP10 caspase 10, apoptosis-related cysteine peptidase
CLC Charcot-Leyden crystal galectin
DENND1B DENN/MADD domain containing 1B
EFNA1 ephrin-A1
ENSA endosulfine alpha
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
F13A1 coagulation factor XIII, A1 polypeptide
FGFR2 fibroblast growth factor receptor 2
GPNMB glycoprotein (transmembrane) nmb
GRB7 growth factor receptor-bound protein 7
HEPH hephaestin
HSPA4 heat shock 70kDa protein 4
IGL immunoglobulin lambda locus
IPO13 importin 13
KRT20 keratin 20, type I
LOC100272216 uncharacterized LOC100272216
LYZ lysozyme
MAOA monoamine oxidase A
MFAP5 microfibrillar associated protein 5
MXI1 MAX interactor 1, dimerization protein
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NT5E 5'-nucleotidase, ecto (CD73)
PAWR PRKC, apoptosis, WT1, regulator
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PRSS2 protease, serine, 2 (trypsin 2)
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
S100A8 S100 calcium binding protein A8
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SCN3A sodium channel, voltage gated, type III alpha subunit
SI sucrase-isomaltase (alpha-glucosidase)
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SMAD1 SMAD family member 1
SNX13 sorting nexin 13
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TOX3 TOX high mobility group box family member 3
TPD52 tumor protein D52
TRIM2 tripartite motif containing 2
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF586 zinc finger protein 586

decreased expression

Symbol Name
ACOT9 acyl-CoA thioesterase 9
ACTB actin, beta
AK1 adenylate kinase 1
AKR1C2 aldo-keto reductase family 1, member C2
ANXA5 annexin A5
CCL19 chemokine (C-C motif) ligand 19
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
COL13A1 collagen, type XIII, alpha 1
DLC1 DLC1 Rho GTPase activating protein
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
F3 coagulation factor III (thromboplastin, tissue factor)
FABP4 fatty acid binding protein 4, adipocyte
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FLRT2 fibronectin leucine rich transmembrane protein 2
FPGS folylpolyglutamate synthase
G0S2 G0/G1 switch 2
GAL galanin/GMAP prepropeptide
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
HSPB8 heat shock 22kDa protein 8
IGFBP4 insulin-like growth factor binding protein 4
LAMP5 lysosomal-associated membrane protein family, member 5
LHFP lipoma HMGIC fusion partner
MAGED1 melanoma antigen family D1
MARCKS myristoylated alanine-rich protein kinase C substrate
MATN2 matrilin 2
MEX3C mex-3 RNA binding family member C
NAMPT nicotinamide phosphoribosyltransferase
NR2F1 nuclear receptor subfamily 2, group F, member 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLTP phospholipid transfer protein
RAP2A RAP2A, member of RAS oncogene family
RBP1 retinol binding protein 1, cellular
S100A2 S100 calcium binding protein A2
SACS sacsin molecular chaperone
TGM2 transglutaminase 2
TSPAN3 tetraspanin 3
TSPYL5 TSPY-like 5
UFM1 ubiquitin-fold modifier 1
WFDC2 WAP four-disulfide core domain 2
WWTR1 WW domain containing transcription regulator 1