BRD-A10662413_Prenylamine lactate_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

99 genes differentially expressed following the BRD-A10662413_Prenylamine lactate_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALB albumin
ATF3 activating transcription factor 3
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BTG2 BTG family, member 2
CD200 CD200 molecule
CD9 CD9 molecule
CFI complement factor I
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHN1 chimerin 1
CHN2 chimerin 2
COL11A1 collagen, type XI, alpha 1
COL4A5 collagen, type IV, alpha 5
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FHOD3 formin homology 2 domain containing 3
FILIP1L filamin A interacting protein 1-like
FN1 fibronectin 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GAGE3 G antigen 3
GLS glutaminase
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
IGFBP7 insulin-like growth factor binding protein 7
IL1R1 interleukin 1 receptor, type I
LEF1 lymphoid enhancer-binding factor 1
LOC100505650 uncharacterized LOC100505650
MAN1A1 mannosidase, alpha, class 1A, member 1
MMP1 matrix metallopeptidase 1
MMP7 matrix metallopeptidase 7
NCALD neurocalcin delta
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NT5E 5'-nucleotidase, ecto (CD73)
NUSAP1 nucleolar and spindle associated protein 1
OBSL1 obscurin-like 1
PAWR PRKC, apoptosis, WT1, regulator
PEA15 phosphoprotein enriched in astrocytes 15
PEG10 paternally expressed 10
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
POLR1C polymerase (RNA) I polypeptide C, 30kDa
POSTN periostin, osteoblast specific factor
PROM1 prominin 1
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
QPCT glutaminyl-peptide cyclotransferase
RGS16 regulator of G-protein signaling 16
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RNF43 ring finger protein 43
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SMYD2 SET and MYND domain containing 2
SPON1 spondin 1, extracellular matrix protein
SULF1 sulfatase 1
TGFBI transforming growth factor, beta-induced, 68kDa
THBS2 thrombospondin 2
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TPD52L1 tumor protein D52-like 1
TRIM2 tripartite motif containing 2
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
AK1 adenylate kinase 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AQP3 aquaporin 3 (Gill blood group)
BST2 bone marrow stromal cell antigen 2
C1QA complement component 1, q subcomponent, A chain
CA12 carbonic anhydrase XII
CD24 CD24 molecule
CDC42SE1 CDC42 small effector 1
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRYAB crystallin, alpha B
CTSW cathepsin W
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL14 chemokine (C-X-C motif) ligand 14
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLD dihydrolipoamide dehydrogenase
EDF1 endothelial differentiation-related factor 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GRWD1 glutamate-rich WD repeat containing 1
HN1 hematological and neurological expressed 1
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
ITM2A integral membrane protein 2A
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
NTS neurotensin
PLAC8 placenta-specific 8
PLTP phospholipid transfer protein
PNMA1 paraneoplastic Ma antigen 1
PRDX2 peroxiredoxin 2
RHOD ras homolog family member D
RPL36 ribosomal protein L36
RPL37A ribosomal protein L37a
S100A11 S100 calcium binding protein A11
SKP1 S-phase kinase-associated protein 1
SLPI secretory leukocyte peptidase inhibitor
STOM stomatin
TES testin LIM domain protein
TFF1 trefoil factor 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
VWF von Willebrand factor
ZMYM2 zinc finger, MYM-type 2