BRD-A10523515_HY-11000_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-A10523515_HY-11000_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMD1 adenosylmethionine decarboxylase 1
ANXA5 annexin A5
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
CCL20 chemokine (C-C motif) ligand 20
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CST3 cystatin C
FLNA filamin A, alpha
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOXC6 homeobox C6
LTBP3 latent transforming growth factor beta binding protein 3
PEBP1 phosphatidylethanolamine binding protein 1
PI3 peptidase inhibitor 3, skin-derived
RBM47 RNA binding motif protein 47
REG1A regenerating islet-derived 1 alpha
RFX5 regulatory factor X, 5 (influences HLA class II expression)
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SLC44A4 solute carrier family 44, member 4
SLIRP SRA stem-loop interacting RNA binding protein
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TSPAN8 tetraspanin 8
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)

decreased expression

Symbol Name
ADGRF5 adhesion G protein-coupled receptor F5
ANGPTL2 angiopoietin-like 2
ARMCX2 armadillo repeat containing, X-linked 2
AURKB aurora kinase B
BAX BCL2-associated X protein
CD93 CD93 molecule
CORO1A coronin, actin binding protein, 1A
CPA3 carboxypeptidase A3 (mast cell)
CPNE3 copine III
CX3CR1 chemokine (C-X3-C motif) receptor 1
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
ELAVL1 ELAV like RNA binding protein 1
FAM129A family with sequence similarity 129, member A
FHOD3 formin homology 2 domain containing 3
FRS2 fibroblast growth factor receptor substrate 2
GEM GTP binding protein overexpressed in skeletal muscle
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HIST1H4C histone cluster 1, H4c
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IL1B interleukin 1, beta
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
KIAA0196 KIAA0196
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
MAN2A1 mannosidase, alpha, class 2A, member 1
MEIS2 Meis homeobox 2
MFAP2 microfibrillar-associated protein 2
MPZL2 myelin protein zero-like 2
NID1 nidogen 1
PRTN3 proteinase 3
RAD21 RAD21 homolog (S. pombe)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RGCC regulator of cell cycle
RGS16 regulator of G-protein signaling 16
RHOBTB3 Rho-related BTB domain containing 3
RSU1 Ras suppressor protein 1
SULF1 sulfatase 1
TGFB3 transforming growth factor, beta 3
UBE2J1 ubiquitin-conjugating enzyme E2, J1
VEGFA vascular endothelial growth factor A
WFDC1 WAP four-disulfide core domain 1
ZIC1 Zic family member 1