BRD-A10523515_HY-11000_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

62 genes differentially expressed following the BRD-A10523515_HY-11000_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AHNAK AHNAK nucleoprotein
AKAP7 A kinase (PRKA) anchor protein 7
ANPEP alanyl (membrane) aminopeptidase
C6ORF48 chromosome 6 open reading frame 48
CST3 cystatin C
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
F5 coagulation factor V (proaccelerin, labile factor)
FLNA filamin A, alpha
GLRX glutaredoxin (thioltransferase)
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IL17RB interleukin 17 receptor B
IRS2 insulin receptor substrate 2
KRT18 keratin 18, type I
KRT7 keratin 7, type II
LTBP3 latent transforming growth factor beta binding protein 3
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SOX9 SRY (sex determining region Y)-box 9
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TSPAN4 tetraspanin 4
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ANGPTL2 angiopoietin-like 2
ARMCX1 armadillo repeat containing, X-linked 1
ARMCX2 armadillo repeat containing, X-linked 2
ATP2A3 ATPase, Ca++ transporting, ubiquitous
AUTS2 autism susceptibility candidate 2
C7 complement component 7
CADM1 cell adhesion molecule 1
CD36 CD36 molecule (thrombospondin receptor)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLEC2B C-type lectin domain family 2, member B
CORO1A coronin, actin binding protein, 1A
CRELD2 cysteine-rich with EGF-like domains 2
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DPYSL3 dihydropyrimidinase-like 3
FABP4 fatty acid binding protein 4, adipocyte
G0S2 G0/G1 switch 2
IL1B interleukin 1, beta
JAM3 junctional adhesion molecule 3
LUM lumican
MBP myelin basic protein
MEF2C myocyte enhancer factor 2C
MREG melanoregulin
MZB1 marginal zone B and B1 cell-specific protein
NES nestin
PCDH7 protocadherin 7
PLN phospholamban
PLVAP plasmalemma vesicle associated protein
RGCC regulator of cell cycle
RGS5 regulator of G-protein signaling 5
SGCE sarcoglycan, epsilon
SPARCL1 SPARC-like 1 (hevin)
TGFB3 transforming growth factor, beta 3
TNS3 tensin 3
TYRP1 tyrosinase-related protein 1
UBE2J1 ubiquitin-conjugating enzyme E2, J1
VWF von Willebrand factor
WFDC1 WAP four-disulfide core domain 1