BRD-A10523515_HY-11000_SKB_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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42 genes differentially expressed following the BRD-A10523515_HY-11000_SKB_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
AHNAK AHNAK nucleoprotein
C1R complement component 1, r subcomponent
C1S complement component 1, s subcomponent
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CD59 CD59 molecule, complement regulatory protein
CFD complement factor D (adipsin)
CST3 cystatin C
DDIT4 DNA-damage-inducible transcript 4
HOXC6 homeobox C6
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IGFBP6 insulin-like growth factor binding protein 6
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
LEPR leptin receptor
MSX1 msh homeobox 1
NPC2 Niemann-Pick disease, type C2
PURA purine-rich element binding protein A
QDPR quinoid dihydropteridine reductase
RAD23B RAD23 homolog B (S. cerevisiae)
RRAGD Ras-related GTP binding D
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SRPX sushi-repeat containing protein, X-linked
SRSF5 serine/arginine-rich splicing factor 5
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMED3 transmembrane emp24 protein transport domain containing 3
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMIGO2 adhesion molecule with Ig-like domain 2
BTG3 BTG family, member 3
CD200 CD200 molecule
CXADR coxsackie virus and adenovirus receptor
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
IGFBP3 insulin-like growth factor binding protein 3
MSMB microseminoprotein, beta-
NXN nucleoredoxin
PTGER3 prostaglandin E receptor 3 (subtype EP3)
SOX11 SRY (sex determining region Y)-box 11
THBS1 thrombospondin 1
TMSB15A thymosin beta 15a