BRD-A10523515_HY-11000_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

20 genes differentially expressed following the BRD-A10523515_HY-11000_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1C2 aldo-keto reductase family 1, member C2
C1S complement component 1, s subcomponent
CTSV cathepsin V
EYA2 EYA transcriptional coactivator and phosphatase 2
GCLC glutamate-cysteine ligase, catalytic subunit
LTF lactotransferrin
LY75 lymphocyte antigen 75
SFRP1 secreted frizzled-related protein 1
TACSTD2 tumor-associated calcium signal transducer 2

decreased expression

Symbol Name
DKK3 dickkopf WNT signaling pathway inhibitor 3
DUOX2 dual oxidase 2
FOSL1 FOS-like antigen 1
FXYD6 FXYD domain containing ion transport regulator 6
IER3 immediate early response 3
IL32 interleukin 32
NXN nucleoredoxin
PON3 paraoxonase 3
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
TACC2 transforming, acidic coiled-coil containing protein 2
TM4SF1 transmembrane 4 L six family member 1