BRD-A10523515_GSK-429286A_PC3_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

82 genes differentially expressed following the BRD-A10523515_GSK-429286A_PC3_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
ASS1 argininosuccinate synthase 1
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
BAG2 BCL2-associated athanogene 2
BPHL biphenyl hydrolase-like (serine hydrolase)
CCL8 chemokine (C-C motif) ligand 8
CHRDL1 chordin-like 1
COBL cordon-bleu WH2 repeat protein
COCH cochlin
CRY1 cryptochrome circadian clock 1
CXCL13 chemokine (C-X-C motif) ligand 13
CYCS cytochrome c, somatic
FABP1 fatty acid binding protein 1, liver
FAM129A family with sequence similarity 129, member A
FBLN5 fibulin 5
GPM6B glycoprotein M6B
GREM1 gremlin 1, DAN family BMP antagonist
IGHM immunoglobulin heavy constant mu
ITM2A integral membrane protein 2A
KLRB1 killer cell lectin-like receptor subfamily B, member 1
LRRC8D leucine rich repeat containing 8 family, member D
MEIS1 Meis homeobox 1
MMD monocyte to macrophage differentiation-associated
MMP11 matrix metallopeptidase 11
MT1F metallothionein 1F
MT1M metallothionein 1M
MT1X metallothionein 1X
MXRA7 matrix-remodelling associated 7
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NID2 nidogen 2 (osteonidogen)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLAT plasminogen activator, tissue
PRAME preferentially expressed antigen in melanoma
PROM1 prominin 1
RNF144A ring finger protein 144A
SFRP1 secreted frizzled-related protein 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TMEM158 transmembrane protein 158 (gene/pseudogene)
VDAC1 voltage-dependent anion channel 1
ZNF131 zinc finger protein 131

decreased expression

Symbol Name
ABI1 abl-interactor 1
ADIRF adipogenesis regulatory factor
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ARHGAP12 Rho GTPase activating protein 12
ARMCX2 armadillo repeat containing, X-linked 2
BSG basigin (Ok blood group)
BST2 bone marrow stromal cell antigen 2
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CCND1 cyclin D1
CDC42 cell division cycle 42
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CNTNAP2 contactin associated protein-like 2
DHRS2 dehydrogenase/reductase (SDR family) member 2
EMX2 empty spiracles homeobox 2
ENO1 enolase 1, (alpha)
GSTT1 glutathione S-transferase theta 1
HOPX HOP homeobox
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
MARCKS myristoylated alanine-rich protein kinase C substrate
PARD3 par-3 family cell polarity regulator
PDGFD platelet derived growth factor D
PMM2 phosphomannomutase 2
SEPP1 selenoprotein P, plasma, 1
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMCO4 single-pass membrane protein with coiled-coil domains 4
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TKT transketolase
TM9SF3 transmembrane 9 superfamily member 3
TPM4 tropomyosin 4
WAC WW domain containing adaptor with coiled-coil
WSB1 WD repeat and SOCS box containing 1
YME1L1 YME1-like 1 ATPase
ZNF395 zinc finger protein 395
ZNF589 zinc finger protein 589