BRD-A10523515_GSK-429286A_HA1E_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

79 genes differentially expressed following the BRD-A10523515_GSK-429286A_HA1E_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANO1 anoctamin 1, calcium activated chloride channel
C4BPA complement component 4 binding protein, alpha
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP2 dual specificity phosphatase 2
DUSP5 dual specificity phosphatase 5
EGR1 early growth response 1
EGR2 early growth response 2
ESR1 estrogen receptor 1
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRAMD4 GRAM domain containing 4
GRB14 growth factor receptor-bound protein 14
HIST1H1C histone cluster 1, H1c
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IFI27 interferon, alpha-inducible protein 27
IGL immunoglobulin lambda locus
IRF8 interferon regulatory factor 8
METTL7A methyltransferase like 7A
MX1 MX dynamin-like GTPase 1
NELL2 NEL-like 2 (chicken)
NME4 NME/NM23 nucleoside diphosphate kinase 4
NPY1R neuropeptide Y receptor Y1
NR4A2 nuclear receptor subfamily 4, group A, member 2
PEG3 paternally expressed 3
PTCH1 patched 1
PTGES prostaglandin E synthase
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
REEP1 receptor accessory protein 1
RPS11 ribosomal protein S11
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SIK1 salt-inducible kinase 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SORD sorbitol dehydrogenase
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SYNE2 spectrin repeat containing, nuclear envelope 2
TGM2 transglutaminase 2
WASL Wiskott-Aldrich syndrome-like
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ACSL3 acyl-CoA synthetase long-chain family member 3
ATF5 activating transcription factor 5
BZW2 basic leucine zipper and W2 domains 2
CAV1 caveolin 1, caveolae protein, 22kDa
CHN1 chimerin 1
CSRP1 cysteine and glycine-rich protein 1
CXCL14 chemokine (C-X-C motif) ligand 14
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
ENOPH1 enolase-phosphatase 1
FAM107A family with sequence similarity 107, member A
FBXL12 F-box and leucine-rich repeat protein 12
FILIP1L filamin A interacting protein 1-like
FNBP1 formin binding protein 1
GREM1 gremlin 1, DAN family BMP antagonist
HAT1 histone acetyltransferase 1
IGF1R insulin-like growth factor 1 receptor
ITGAV integrin, alpha V
MYL9 myosin, light chain 9, regulatory
PAM peptidylglycine alpha-amidating monooxygenase
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PTX3 pentraxin 3, long
S100A7 S100 calcium binding protein A7
S100A9 S100 calcium binding protein A9
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SQLE squalene epoxidase
SYNM synemin, intermediate filament protein
TFRC transferrin receptor
TIMP3 TIMP metallopeptidase inhibitor 3
TUBB2B tubulin, beta 2B class IIb