BRD-A10523515_GSK-429286A_HA1E_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-A10523515_GSK-429286A_HA1E_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AKR1C3 aldo-keto reductase family 1, member C3
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
COBL cordon-bleu WH2 repeat protein
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GDF15 growth differentiation factor 15
HBB hemoglobin, beta
HLA-C major histocompatibility complex, class I, C
HOXA10 homeobox A10
KAZN kazrin, periplakin interacting protein
KDM5D lysine (K)-specific demethylase 5D
MAP3K5 mitogen-activated protein kinase kinase kinase 5
METTL7A methyltransferase like 7A
MID1IP1 MID1 interacting protein 1
MTCL1 microtubule crosslinking factor 1
NELL2 NEL-like 2 (chicken)
NQO1 NAD(P)H dehydrogenase, quinone 1
NRIP1 nuclear receptor interacting protein 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SOX9 SRY (sex determining region Y)-box 9
TFF3 trefoil factor 3 (intestinal)
VCAM1 vascular cell adhesion molecule 1
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ATF3 activating transcription factor 3
BHLHE41 basic helix-loop-helix family, member e41
CADM1 cell adhesion molecule 1
CCND1 cyclin D1
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CKAP4 cytoskeleton-associated protein 4
CLIC5 chloride intracellular channel 5
COL11A1 collagen, type XI, alpha 1
CRABP2 cellular retinoic acid binding protein 2
CTSE cathepsin E
CYCS cytochrome c, somatic
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
ELAVL1 ELAV like RNA binding protein 1
FABP7 fatty acid binding protein 7, brain
GADD45B growth arrest and DNA-damage-inducible, beta
GLIPR1 GLI pathogenesis-related 1
GNAS GNAS complex locus
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IGFBP3 insulin-like growth factor binding protein 3
JAM3 junctional adhesion molecule 3
KRT19 keratin 19, type I
MFAP5 microfibrillar associated protein 5
MXI1 MAX interactor 1, dimerization protein
MYH10 myosin, heavy chain 10, non-muscle
MYL9 myosin, light chain 9, regulatory
NPDC1 neural proliferation, differentiation and control, 1
PAPD7 PAP associated domain containing 7
PLN phospholamban
POSTN periostin, osteoblast specific factor
PTGIS prostaglandin I2 (prostacyclin) synthase
RCAN1 regulator of calcineurin 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
S100A10 S100 calcium binding protein A10
SCG2 secretogranin II
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SULF1 sulfatase 1
TAGLN2 transgelin 2
TCEAL2 transcription elongation factor A (SII)-like 2
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
VTCN1 V-set domain containing T cell activation inhibitor 1
YME1L1 YME1-like 1 ATPase
ZIC1 Zic family member 1